77750-06-2

Basic information

• Product Name: Benzenecarbothioic acid, 4-chloro-, S-(4-methylphenyl) ester
• CAS NO: 77750-06-2
• Molecular Formula: C14H11ClOS
• Molecular Weight: 262.76
• Mol File: 77750-06-2.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: Benzenecarbothioic acid, 4-chloro-, S-(4-methylphenyl) ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenecarbothioic acid, 4-chloro-, S-(4-methylphenyl) ester(77750-06-2)
• EPA Substance Registry System: Benzenecarbothioic acid, 4-chloro-, S-(4-methylphenyl) ester(77750-06-2)

Safety Data

• Hazardous Substances Data: 77750-06-2(Hazardous Substances Data)

Upstream product

• 122-01-0 4-chloro-benzoyl chloride 
• 106-45-6 para-thiocresol 
• 203070-21-7 1-[(4-Chloro-phenyl)-phenylselanyl-p-tolylsulfanyl-methyl]-1H-benzotriazole 
• 201230-82-2 carbon monoxide 
• 104-88-1 4-chlorobenzaldehyde 
• 203070-13-7 1-[(4-Chloro-phenyl)-p-tolylsulfanyl-methyl]-1H-benzotriazole 
• 103-19-5 di(p-tolyl) disulfide 
• 456-21-3 4-chlorobenzoyl fluoride 
• 824-79-3 sodium 4-methylbenzenesulfinate 
• 6343-28-8 1-(4-chlorobenzoyl)pyrrolidine-2,5-dione 
• 74-11-3 para-chlorobenzoic acid 
• 1679-18-1 4-Chlorophenylboronic acid 
• 98-59-9 p-toluenesulfonyl chloride 
• 13939-06-5 molybdenum hexacarbonyl 

Downstream Products

• 165543-77-1 4-Chloro-dithiobenzoic acid p-tolyl ester 
• 53144-72-2 (4-chlorobenzyl)diphenylphosphine oxide 
• 22865-55-0 (4-chlorophenyl)(4-methylphenyl)sulfane 
• 6833-15-4 4-chlorobenzanilide 
• 4018-82-0 4-chloro-N-(4-methoxyphenyl)benzamide 
• 39193-06-1 4,4'-dichlorobenzanilide 
• 2447-95-2 4-chloro-N-(4-tolyl)benzamide 

Relevant articles and documents

Method for synthesizing thioester through cross-coupling of visible light-catalyzed sodium sulfinate and acyl chloride

The method takes sodium sulfinate and acyl chloride as raw materials and utilizes 2, 6 - dimethyl -1, 4 - dihydro -3, 5 - pyridine dicarboxylic acid diethyl ester and an organic alkali catalytic system to cross-couple sulfur radicals and acyl radicals und

Nickel-Catalyzed Thiocarbonylation of Arylboronic Acids with Sulfonyl Chlorides for the Synthesis of Thioesters

An interesting procedure for thioester synthesis via nickel-catalyzed thiocarbonylation of arylboronic acid with sulfonyl chlorides as the sulfur source has been explored. Using Mo(CO)6 as a solid CO surrogate and reductant, a broad range of thioesters were obtained in moderate to good yields with good functional group tolerance.

Oxalic Acid Monothioester for Palladium-Catalyzed Decarboxylative Thiocarbonylation and Hydrothiocarbonylation

Oxalic acid monothioester (OAM), an easily accessible and storable reagent, was reported herein as a thioester synthetic equivalent for palladium-catalyzed decarboxylative thiocarbonylation of organohalides and hydrothiocarbonylation of unsaturated carbon-carbon bonds at room temperature with high chemo- and regioselectivity. The reaction is applicable to the synthesis of cysteine-derived thioesters, thus allowing chemical modification of cysteine-containing peptides. Decarboxylation of OAM proceeds through oxidative addition of Pd(0) to the acyl-S bond, which accounts for the very mild reaction conditions.