77772-21-5Relevant articles and documents
Lewis Acid-Activated Reactions of Silyl Ketenes for the Preparation of α-Silyl Carbonyl Compounds
Mitchell, Sarah M.,Xiang, Yuanhui,Matthews, Rachael,Amburgey, Alexis M.,Pentzer, Emily B.
, (2019/11/14)
Silyl-substituted ketenes are attractive molecular building blocks due to their stability and ease of storage, as opposed to unstable alkyl and aryl ketenes. To better understand the reactivity of silyl ketenes and, in turn, their use in the preparation o
Synthesis and Application of Bis-Silylethyl-Derived Phosphate-Protected Fmoc-Phosphotyrosine Derivatives for Peptide Synthesis
Chao, Hann-Guang,Bernatowicz, Michael S.,Reiss, Paul D.,Matsueda, Gary R.
, p. 6687 - 6691 (2007/10/02)
Three Fmoc-phosphotyrosine derivatives with silylethyl-based phosphate protection were synthesized and evaluated for use in peptide synthesis.The stability of these derivatives toward piperidine/DMF (1:4) treatment and their cleavability with TFA solutions were examined.On the basis of these data, the bis-protected Fmoc-phosphotyrosine derivative or Fmoc-Tyr(PO3MDPSE2)-OH, was shown to be the most suitable candidate for the production of phosphotyrosine peptides.The syntheses of phosphotyrosine peptides including one containing Met and Cys are described.
STUDIES ON THE STEREOSELECTIVITY OF THE PREPARATION OF α,β-UNSATURATED ESTERS FROM α-LITHIO-α-SILYL ESTERS
Larson, Gerald L.,Quiroz, Fernando,Suarez, Juan
, p. 833 - 844 (2007/10/02)
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