78134-18-6Relevant articles and documents
An Electrochemical Way to Generate Amphiphiles from Hydrazones for the Synthesis of 1,2,4-Triazole Scaffold Cyclic Compounds
Li, Wangyu,Liang, Xiao,Pan, Yuanjiang,Wang, Dungai,Xiong, Mingteng,Zhu, Heping
, (2022/02/02)
An electro-oxidative cyclization pathway in which hydrazones are selected as starting materials to generate amphiphiles by reacting with benzylamines and benzamides was reported. This strategy successfully prepared a series of 1,2,4-triazoles in satisfact
On the Reaction of Isocyanides with Nitrile Imines
Moderhack, Dietrich,Lorke, Michael,Ernst, Ludger,Schomburg, Dietmar
, p. 1633 - 1640 (2007/10/02)
Four competing reactions have been found to occur when nitrile imines 2 are generated from 1 in the presence of isocyanides 3.The products obtained include i) 1,2,3-triazolium salts 6, ii) 1,2,4-triazolium salts 8, iii) dihydrotriazolyl-substituted pyrazolamines 11, and iv) unstable 1,2-diazetimine derivatives 12 which in turn give carbodiimides 13, nitriles 14, quinoxalinamines 15, and possibly 1,2,4-triazoles 16 (after addition of 2).The proportions, in particular those of 6,8, and 11, depend on the reaction conditions; thus, triethylamine used in excess can oppress the formation of 6 in favour of 8 and 11. - The structure of 11 has been elucidated by means of X-ray diffraction analyses of 11a and c. - Key Words: Isocyanides / Nitrile imines / Triazolium salts / Pyrazoles / 1,2-Diazet-3-imines
1H-1,2,4-Triazole 2-oxide from O-benzoyl derivatives of N-Substituted benzamidoximes and benzonitrile oxide
Foti, Francesco,Grassi, Giovanni,Risitano, Francesco,Caruso, Francesco
, p. 3048 - 3054 (2007/10/02)
Treatment of the readily prepared O-benzoyl derivatives of N-substituted benzamidoximes with benzonitrile oxide gave 1H-1,2,4-triazole 2-oxides.
