78386-53-5Relevant articles and documents
Solvolytic Rearrangements of Azabicyclic Compounds. Part 2. Kinetics
Bastable, John W.,Dunkin, Ian R.,Hobson, John D.
, p. 1346 - 1351 (2007/10/02)
Rates of solvolysis in aqueous ethanol and aqueous dioxan of three 2-exo-chloroazabicycloalkanes have been studied and first-order rare constants are derived and compared with published values for analogous compounds.Anchimeric assistance by the bridge N-atom is evidently not important in the rate-controlling step in these rearrangements, though it may occur to a minor extent in the case of 2-exo-chloro-7-methyl-7-azanorbornane.Solvolytic results for tropan-2β-yl toluene-p-sulphonate in aqueous ethanol and aqueous acetone mixtures are also reported and compared with literature data for the carbobicyclic and oxabicyclic analogues.
