78469-76-8

Basic information

• Product Name: (2R,3R)-1-benzyloxy-3,4-epoxy-2-(1'-methoxy-1'-methylaethoxy)-butan
• Synonyms: (2R,3R)-1-benzyloxy-3,4-epoxy-2-(1'-methoxy-1'-methylaethoxy)-butan
• CAS NO: 78469-76-8
• Molecular Weight: 266.337
• Mol File: 78469-76-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2R,3R)-1-benzyloxy-3,4-epoxy-2-(1'-methoxy-1'-methylaethoxy)-butan(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3R)-1-benzyloxy-3,4-epoxy-2-(1'-methoxy-1'-methylaethoxy)-butan(78469-76-8)
• EPA Substance Registry System: (2R,3R)-1-benzyloxy-3,4-epoxy-2-(1'-methoxy-1'-methylaethoxy)-butan(78469-76-8)

Safety Data

• Hazardous Substances Data: 78469-76-8(Hazardous Substances Data)

Upstream product

• 116-11-0 2-Methoxypropene 
• 72229-13-1 (2R,3R)-1-benzyloxy-3,4-epoxy-2-butanol 
• 627-40-7 methylallylether 
• 78469-78-0 (4R,5R)-p-toluolsulfonsaeure<(5-benzyloxymethyl-5-hydroxymethyl-2,2-dimethyl-1,3-dioxolan-4-yl)methyl>ester 
• 100-39-0 benzyl bromide 
• 78469-77-9 1-O-benzyl-2,3-O-isopropylidene-D-threitol 
• 78469-75-7 (2R,3R)-p-nitrobenzoesaeure-(1-benzyloxy-3,4-epoxy-2-butyl)ester 
• 78469-79-1 Toluene-4-sulfonic acid (2R,3R)-4-benzyloxy-2,3-dihydroxy-butyl ester 
• 109613-52-7 (R,R)-4-benzyloxy-2,3-dihydroxybutyl methanesulfonate 
• 109613-50-5 (R,R)-4-benzyloxy-2,3-bis(1-ethoxyethoxy)-1-butanol 
• 109613-51-6 (R,R)-4-benzyloxy-2,3-bis(1-ethoxyethoxy)butyl methanesulfonate 

Downstream Products

• 91526-98-6 benzyl (4R,5R)-2,2-dimethyl-5-(2-methyl-1,3-dithian-2-ylmethyl)-1,3-dioxolan-4-ylmethyl ether 
• 91526-99-7 1-((4R,5R)-5-((benzyloxy)methyl)-2,2-dimethyl-1,3-dioxolan-4-yl)propane-2-one 

Relevant articles and documents

Total synthesis of (+)-colletodiol from (S,S)-tartrate and (R)-3-hydroxybutanoate

The macrodiolide antibiotic (+)-colletodiol (7, Scheme 1) was synthesised.The configuration was thus proven to be (6R,11R,12R,14R). - Key intermediates (Schemes 9 and 10) are the two hydroxy acids 43 and 64, which were prepared from dimethyl (S,S)-tartrate in 20percent overall yield (12 steps) and from (R)-3-hydroxybutanoate in 57percent overall yield (6 steps), respectively.The two hydroxy acids were cyclised to give, after deprotection, the title compound. - Our investigations led to the production of a large number of chiral building blocks, many of them in different stereoisomeric forms.