78469-78-0Relevant articles and documents
Formal synthesis of (+)-isolaurepinnacin
Suzuki, Toshio,Matsumura, Ryuji,Oku, Ken-ichi,Taguchi, Keiichi,Hagiwara, Hisahiro,Hoshi, Takashi,Ando, Masayoshi
, p. 65 - 67 (2007/10/03)
The stereoselective formal synthesis of (+)-isolaurepinnacin is described. The required key oxepene skeleton possessing cis-oriented alkyl substituents at the α,ω-positions was stereoselectively constructed via the cyclization of the corresponding hydroxy epoxide promoted by the (Bu3Sn)2O/Zn(OTf)2 system.
Chiral Electrophilic Synthetic Building Blocks with Four Different Functional Groups from Tartaric Acid, 2,3- and 3,4-Epoxy-butanediol Derivatives in All Four Stereoisomeric Forms
Hungerbuehler, Ernst,Seebach, Dieter
, p. 687 - 702 (2007/10/02)
Efficient and simple procedures have been developed for the preparation of the threo- and erythro-3,4-epoxy-1,2-butanediol derivatives 7 and 9 in both enantiomeric forms from tartaric acid.These epoxides should prove versatile as alkylating reagents in sy