78817-83-1 Usage
Molecular weight
290.7 The molecular weight of lorazepam is the mass of one mole of the compound, calculated by adding the atomic weights of all the atoms in the molecular formula.
Chemical structure
1,4-Benzodiazepine derivative Lorazepam is a derivative of the 1,4-benzodiazepine class of compounds, which are characterized by a fused ring structure consisting of two nitrogen atoms and a seven-membered ring.
Functional groups
Carboxylic acid, phenyl ester Lorazepam contains a carboxylic acid group (-COOH) and a phenyl ester group (-OC2H5), which contribute to its pharmacological properties.
Optical isomer
(3R)The (3R)designation indicates the configuration of the lorazepam molecule, which is important for its activity and efficacy.
Therapeutic uses
Anxiety disorders, insomnia, acute seizures Lorazepam is primarily used to treat these conditions by enhancing the effects of GABA in the brain.
Administration
Oral, injection Lorazepam can be administered orally or through injection, allowing for flexibility in treatment options.
Onset and duration of action
Within minutes to hours, up to 12 hours The effects of lorazepam are felt quickly and can last for up to 12 hours, depending on the individual and the dose.
Risks
Dependence, abuse, withdrawal symptoms, addiction Prolonged use of lorazepam can lead to physical and psychological dependence, as well as the potential for abuse and addiction. It is important to use this medication under the guidance of a healthcare professional to minimize these risks.
Check Digit Verification of cas no
The CAS Registry Mumber 78817-83-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,8,8,1 and 7 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 78817-83:
(7*7)+(6*8)+(5*8)+(4*1)+(3*7)+(2*8)+(1*3)=181
181 % 10 = 1
So 78817-83-1 is a valid CAS Registry Number.
78817-83-1Relevant articles and documents
NEW CHIRAL STATIONARY PHASES FOR CHROMATOGRAPHY BASED ON AROMATIC ALLYL AMINES
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Page/Page column 16-17; Figure 6, (2009/10/22)
New chiral stationary phases (CSPs) based on chiral selectors covalently bound on a solid support were prepared. Chiral selectors were obtained from enantiomerically pure aromatic amines and 3,5-dinitrobenzoic acid and then linked to the support surface through the allylic double bond. Such obtained materials allow enantioseparation of racemates or enantiomerically enriched compounds. These chiral stationary phases can be used as fillings in chromatographic columns for enantiomer separation of naproxen type drugs and other similar non-steroidal anti-inflammatory drugs (NSAID) by means of high performance liquid chromatography on both the analytical and preparative scale.
