791053-96-8

Basic information

• Product Name: Ethanone, 2-bromo-2-(2-fluoro-4-pyridinyl)-1-(3-methylphenyl)-
• CAS NO: 791053-96-8
• Molecular Formula: C14H11BrFNO
• Molecular Weight: 308.15
• Mol File: 791053-96-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Ethanone, 2-bromo-2-(2-fluoro-4-pyridinyl)-1-(3-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 2-bromo-2-(2-fluoro-4-pyridinyl)-1-(3-methylphenyl)-(791053-96-8)
• EPA Substance Registry System: Ethanone, 2-bromo-2-(2-fluoro-4-pyridinyl)-1-(3-methylphenyl)-(791053-96-8)

Safety Data

• Hazardous Substances Data: 791053-96-8(Hazardous Substances Data)

Upstream product

• 303162-49-4 2-(2-fluoro-pyridin-4-yl)-1-(3-methylphenyl)ethanone 
• 21384-43-0 1-(3-methylbenzoyl)-2-methylaziridine 
• 461-87-0 2-fluoro-4-methylpyridine 

Downstream Products

• 896737-10-3 6-chloro-3-(2-fluoropyridin-4-yl)-2-(3-methylphenyl)imidazo[1,2-b]pyridazine 
• 896740-01-5 6-Chloro-3-(2-ethoxypyridin-4-yl)-2-(3-methylphenyl)imidazo[1,2-b]pyridazine 
• 365428-57-5 2-ethyl-5-(2-fluoro-pyridin-4-yl)-4-(3-methylphenyl)-1,3-thiazole 

Relevant articles and documents

CONDENSED IMIDAZOLE COMPOUND AND USE THEREOF

The present invention relates to a compound represented by the formula [I] wherein X1, X2 and X3 are each an optionally substituted CH or a nitrogen atom, and any one of X1, X2 and X3 is a nitrogen atom, X4 is an optionally substituted CH, R1 is an optionally substituted phenyl group or an optionally substituted heterocyclic group, and R2 is an optionally substituted pyridin-4-yl group, an optionally substituted pyridine-N-oxide-4-yl group or an optionally substituted pyrimidin-4-yl group, or a salt thereof. The compound has superior p38 MAP kinase inhibitory activity and MMP-13 production inhibitory activity, and is useful as an agent for the prophylaxis or treatment and the like of an inflammatory disease, an autoimmune disease, a debilitating disease, an osteoarticular degenerative disease, a neurodegenerative disease, a vascular disease, a neoplastic disease or an infectious disease.