792936-55-1

Basic information

• Product Name: (3-fluoro-4-methoxy-5-nitro-benzyl)-phosphonic acid diethyl ester
• Synonyms: (3-fluoro-4-methoxy-5-nitro-benzyl)-phosphonic acid diethyl ester
• CAS NO: 792936-55-1
• Molecular Weight: 321.242
• Mol File: 792936-55-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (3-fluoro-4-methoxy-5-nitro-benzyl)-phosphonic acid diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (3-fluoro-4-methoxy-5-nitro-benzyl)-phosphonic acid diethyl ester(792936-55-1)
• EPA Substance Registry System: (3-fluoro-4-methoxy-5-nitro-benzyl)-phosphonic acid diethyl ester(792936-55-1)

Safety Data

• Hazardous Substances Data: 792936-55-1(Hazardous Substances Data)

Upstream product

• 792936-53-9 1-(bromomethyl)-3-fluoro-4-methoxy-5-nitro-benzene 
• 78-40-0 triethyl phosphate 
• 320-70-7 3-fluoro-4-methoxy-5-nitro-benzaldehyde 
• 792936-51-7 (3-fluoro-4-methoxy-5-nitro-phenyl)methanol 
• 351-54-2 3-fluoro-p-anisaldehyde 
• 122-52-1 triethyl phosphite 

Downstream Products

• 792936-58-4 4-(3-fluoro-4-hydroxy-5-nitro-benzylidene)-piperidine-1-carboxylic acid tert-butyl ester 
• 792936-59-5 4-(3-amino-5-fluoro-4-hydroxy-benzyl)-piperidine-1-carboxylic acid tert-butyl ester 
• 792936-57-3 4-(3-fluoro-4-methoxy-5-nitro-benzylidene)-piperidine-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

ANTIDEPRESSANT HETEROARYL DERIVATIVES OF HETEROCYCLE-FUSED BENZODIOXANS

The invention provides compounds of the Formula: (I) that are useful for the treatment of depression (including but not limited to major depressive disorder, childhood depression and dysthymia), anxiety, panic disorder, post-traumatic stress disorder, premenstrual dysphoric disorder (also known as pre- menstrual syndrome), attention deficit disorder (with and without hyperactivity), obsessive compulsive disorder, social anxiety disorder, generalized anxiety disorder, obesity, eating disorders such as anorexia nervosa, bulimia nervosa, vasomotor flushing, cocaine and alcohol addiction, sexual dysfunction and related illnesses. The compounds are able to block the recptake of serotonin and are modulators at brain 5HT1A serotonin receptors.

BENZOXAZINONE DERIVATIVES, THEIR PREPARATION AND USE

Compounds of formula (I) and pharmaceutically acceptable salts thereof are disclosed, wherein R1 is hydrogen or C1-6alkyl; and R2 is fluoro or chloro. Methods of preparation and uses thereof in treatment of CNS disorders, such as depression or