792936-59-5

Basic information

• Product Name: 4-(3-amino-5-fluoro-4-hydroxy-benzyl)-piperidine-1-carboxylic acid tert-butyl ester
• Synonyms: 4-(3-amino-5-fluoro-4-hydroxy-benzyl)-piperidine-1-carboxylic acid tert-butyl ester
• CAS NO: 792936-59-5
• Molecular Weight: 324.396
• Mol File: 792936-59-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-(3-amino-5-fluoro-4-hydroxy-benzyl)-piperidine-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(3-amino-5-fluoro-4-hydroxy-benzyl)-piperidine-1-carboxylic acid tert-butyl ester(792936-59-5)
• EPA Substance Registry System: 4-(3-amino-5-fluoro-4-hydroxy-benzyl)-piperidine-1-carboxylic acid tert-butyl ester(792936-59-5)

Safety Data

• Hazardous Substances Data: 792936-59-5(Hazardous Substances Data)

Upstream product

• 320-70-7 3-fluoro-4-methoxy-5-nitro-benzaldehyde 
• 792936-51-7 (3-fluoro-4-methoxy-5-nitro-phenyl)methanol 
• 351-54-2 3-fluoro-p-anisaldehyde 
• 792936-57-3 4-(3-fluoro-4-methoxy-5-nitro-benzylidene)-piperidine-1-carboxylic acid tert-butyl ester 
• 792936-55-1 (3-fluoro-4-methoxy-5-nitro-benzyl)-phosphonic acid diethyl ester 
• 792936-53-9 1-(bromomethyl)-3-fluoro-4-methoxy-5-nitro-benzene 
• 792936-58-4 4-(3-fluoro-4-hydroxy-5-nitro-benzylidene)-piperidine-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

3,4-Dihydro-2H-benzoxazinones as dual-acting 5-HT1A receptor antagonists and serotonin reuptake inhibitors

Investigation of halogen substitution in lead compound 1 has led to the identification of analogues which combine high affinity for 5-HT1A receptors and potent serotonin reuptake inhibitory activity. Several compounds show an improved selectivity over 5-HT1B and 5-HT1D receptors and a superior pharmacokinetic profile in the rat.