79432-14-7

Basic information

• Product Name: (2S,5R)-2-amino-6-[(benzyloxycarbonyl)amino]-5-hydroxyhexanoic acid
• Synonyms: (2S,5R)-2-amino-6-[(benzyloxycarbonyl)amino]-5-hydroxyhexanoic acid
• CAS NO: 79432-14-7
• Molecular Weight: 296.323
• Mol File: 79432-14-7.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (2S,5R)-2-amino-6-[(benzyloxycarbonyl)amino]-5-hydroxyhexanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,5R)-2-amino-6-[(benzyloxycarbonyl)amino]-5-hydroxyhexanoic acid(79432-14-7)
• EPA Substance Registry System: (2S,5R)-2-amino-6-[(benzyloxycarbonyl)amino]-5-hydroxyhexanoic acid(79432-14-7)

Safety Data

• Hazardous Substances Data: 79432-14-7(Hazardous Substances Data)

Upstream product

• 96359-88-5 (2S,5R)-6-[(benzyloxycarbonyl)amino]-2-[(tert-butoxycarbonyl)amino]-5-hydroxyheptanoic acid 
• 501-53-1 benzyl chloroformate 
• 2219-28-5 (R)-5-hydroxy-L-lysine dihydrochloride hydrate 
• 504-91-6 (5R)-5-hydroxy-L-lysine 
• 144090-57-3 tert-butyl (S)-4-(but-3-enyl)-2,2-dimethyloxazolidine-3-carboxylate 
• 144090-58-4 (S)-2,2-Dimethyl-4-(2-oxiranyl-ethyl)-oxazolidine-3-carboxylic acid tert-butyl ester 
• 144090-59-5 (S)-4-((S)-4-Azido-3-hydroxy-butyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 144090-61-9 (S)-4-((S)-4-Azido-3-benzyloxy-butyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 

Downstream Products

• 121447-31-2 (2S,5R)-2,6-Bis-benzyloxycarbonylamino-5-hydroxy-hexanoic acid 
• 96261-29-9 dicarbobenzoxy-δ-hydroxy-L-lysine-lactone 
• 254757-73-8 (2S,5R)-6-Benzyloxycarbonylamino-2-(9H-fluoren-9-ylmethoxycarbonylamino)-5-hydroxy-hexanoic acid 
• 96359-88-5 (2S,5R)-6-[(benzyloxycarbonyl)amino]-2-[(tert-butoxycarbonyl)amino]-5-hydroxyheptanoic acid 
• 291279-90-8 (2S,5R)-(-)-tert-butyl-6-[(benzyloxycarbonyl)amino]-2-[(tert-butoxycarbonyl)amino]-5-hydroxyhexanoate 
• 75466-93-2 [(3S,6R)-6-(Benzyloxycarbonylamino-methyl)-2-oxo-tetrahydro-pyran-3-yl]-carbamic acid benzyl ester 
• 86235-37-2 Dicarbobenzoxy-allohydroxylysin-δ-lacton 
• 75466-97-6 dicarbobenzy-δ-hydroxy-L-lysyl-O-t-butylglycyl-O-3,4,6-tri-O-acetyl-β-D-galactopyranoside 
• 75466-96-5 4-Oxo-pentanoic acid (2R,3R,4S,5S,6R)-4,5-diacetoxy-6-acetoxymethyl-2-[(1R,4S)-4-benzyloxycarbonylamino-1-(benzyloxycarbonylamino-methyl)-4-(tert-butoxycarbonylmethyl-carbamoyl)-butoxy]-tetrahydro-pyran-3-yl ester 
• 75477-74-6 {(2S,5R)-2,6-Bis-benzyloxycarbonylamino-5-[(2R,3R,4S,5R,6R)-4,5-dihydroxy-6-hydroxymethyl-3-((2R,3R,4S,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-2-yloxy]-hexanoylamino}-acetic acid 
• 75466-99-8 {(2S,5R)-2,6-Bis-benzyloxycarbonylamino-5-[(2R,3R,4S,5S,6R)-4,5-diacetoxy-6-acetoxymethyl-3-((2R,3R,4S,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-2-yloxy]-hexanoylamino}-acetic acid 
• 75466-98-7 dicarbobenzoxy-δ-hydroxy-L-lysyl-O-t-butylglycyl-O-<2-O-(2,3,4,6-tetra-O-benzyl) α-D-glucopyranosyl>-3,4,6-tri-O-acetyl-β-D-galactopyranoside 
• 79432-06-7 dicarbobenzoxy-δ-hydroxy-L-lysylglycine t-butyl ester 

Relevant articles and documents

9-BBN as a convenient protecting group in functionalisation of hydroxylysine

9-BBN was used for regioselective protection of the α-amino and α-carboxyl groups of (5R)-5-hydroxy-L-lysine. The resulting 9-BBN complex was then employed in transformations such as N-Cbz protection, azido transfer, O-glycosylation, and O-silylation. Further manipulations led to improved methods for preparation of hydroxylysine and galactosylated hydroxylysine building blocks, suitable for direct use in peptide synthesis under standard Fmoc conditions.

Preparation of a diglycosylated hydroxylysine building block used in solid-phase synthesis of a glycopeptide from type II collagen

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SYNTHESIS OF O-(2-O-α-D-GLUCOPYRANOSYL)-β-D-GALACTOPYRANOSIDE OF OPTICALLY PURE δ-HYDROXY-L-LYSYLGLYCINE AND δ-HYDROXY-L-LYSYLGLYCYL-L-GLUTAMYL-L-ASPARATYLGLYCINE. COMPONENTS OF THE GLOMERULAR BASEMENT MEMBRANE

The application of the levulinyl group as a temporary blocking group for the 2-OH function of galactose proved to be very efficient not only for the introduction of a β- linkage between galactose and the optically pure δ-hydroxy-L-lysylglycine, but also t