79598-53-1 Usage
Description
6-Azido-hexanoic acid is a six-carbon saturated fatty acid with an ω-terminal azide group. It is a linker containing an azide group and a terminal carboxylic acid. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. It is a colorless to yellow oil.
Uses
Used in Bioconjugation Applications:
6-Azido-hexanoic acid is used as a linker for bioconjugation, particularly for crosslinking and the synthesis of chemical probes. The terminal azide group allows conjugation with compounds containing alkyne groups through a copper(I)-catalyzed cycloaddition reaction, also known as click chemistry.
Used in Pharmaceutical Industry:
6-Azido-hexanoic acid is used as a building block in the pharmaceutical industry for the synthesis of drug candidates and the development of drug delivery systems. Its ability to form stable amide bonds with primary amine groups in the presence of activators makes it a versatile component in the design and synthesis of new pharmaceutical compounds.
Used in Chemical Synthesis:
6-Azido-hexanoic acid is used as a building block in chemical synthesis for the creation of various chemical probes and conjugates. Its reactivity with primary amine groups and alkyne compounds through click chemistry allows for the development of novel chemical entities with potential applications in research and industry.
Check Digit Verification of cas no
The CAS Registry Mumber 79598-53-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,9,5,9 and 8 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 79598-53:
(7*7)+(6*9)+(5*5)+(4*9)+(3*8)+(2*5)+(1*3)=201
201 % 10 = 1
So 79598-53-1 is a valid CAS Registry Number.
79598-53-1Relevant articles and documents
Solid-Phase Supports and Uses Thereof
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, (2015/09/28)
The present disclosure relates to solid-phase azide supports, methods for making solid-state azide supports, and methods for capturing alkynes using the same. The present disclosure also relates to kits for solid-phase azide supports
