286964-95-2

Basic information

• Product Name: (4S)-3-(6-azido-1-oxohexyl)-4-benzyl-2-oxazolidinone
• Synonyms: (4S)-3-(6-azido-1-oxohexyl)-4-benzyl-2-oxazolidinone
• CAS NO: 286964-95-2
• Molecular Weight: 316.36
• Mol File: 286964-95-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (4S)-3-(6-azido-1-oxohexyl)-4-benzyl-2-oxazolidinone(CAS DataBase Reference)
• NIST Chemistry Reference: (4S)-3-(6-azido-1-oxohexyl)-4-benzyl-2-oxazolidinone(286964-95-2)
• EPA Substance Registry System: (4S)-3-(6-azido-1-oxohexyl)-4-benzyl-2-oxazolidinone(286964-95-2)

Safety Data

• Hazardous Substances Data: 286964-95-2(Hazardous Substances Data)

Upstream product

• 90719-32-7 (S)-4-Benzyl-2-oxazolidinone 
• 4224-70-8 6-bromohexanoic acid 
• 22809-37-6 6-bromohexanoyl chloride 
• 79598-53-1 6-azidohexanoic acid 
• 203739-34-8 (S)-4-benzyl-3-(6-bromo-1-oxohexyl)-2-oxazolidinone 

Downstream Products

• 286964-97-4 (2R)-6-azido-2-benzylhexanoic acid 
• 286964-99-6 (2R)-6-azido-2-benzylhexanoyl-glycyl-glycine ethyl ester 
• 341508-51-8 (2R)-6-N-(tert-butoxycarbonyl)amino-2-benzylhexanoyl-glycyl-glycine 
• 286965-05-7 (2R)-6-N-(tert-butoxycarbonyl)amino-2-benzylhexanoyl-glycyl-glycine ethyl ester 
• 1424402-58-3 C₄₁H₅₄ClN₅O₉ 
• 1424402-68-5 C₃₈H₄₈ClN₅O₈ 
• 1424402-48-1 C₅₈H₆₇Cl₄N₅O₁₂ 
• 1424402-27-6 (R)-5-azido-3-((S)-4-benzyl-2-oxooxazolidine-3-carbonyl)heptanoic acid 
• 1424402-28-7 [(S)-6-azido-2-((R)-4-benzyl-2-oxooxazolidine-3-carbonyl)hexyl]carbamic acid tert-butyl ester 
• 168973-97-5 (4S)-4-benzyl-3-<(2'R)-2'-<(tert-butoxycarbonyl)methyl>-6'-azidohexanoyl>-2-oxazolidone 
• 868248-78-6 (3(2S),4S)-3-(6-azido-2-methyl-1-oxohexyl)-4-benzyl-2-oxazolidinone 
• 286964-96-3 (S)-3-(6-azido-(2R)-benzyl-1-oxohexyl)-4-benzyl-2-oxazolidinone 

Relevant articles and documents

Synthesis and conformation of Gly-Gly dipeptides constrained with phenylalanine-like aminocaproic acid linkers.

[structure: see text] The constraint of dipeptides with linkers derived from 6-aminocaproic acid (Aca) is a useful means of constructing a beta-turn peptidomimetic. The extension of this concept to the mimicry of a tripeptide entails the incorporation of a side chain moiety on either end of the Aca chain. The synthesis and conformational analysis of two exemplary compounds is discussed.

Synthesis of Cα methylated carboxylic acids: Isosteres of arginine and lysine for use as N-terminal capping residues in polypeptides

Replacement of the N-terminal α-amine with the isosteric methyl functionality in bioactive peptides can influence various pharmacokinetic parameters, including hydrophobicity and stability. Cα methylated amino acid analogues are thus of great interest to expand the repertoire of nonnatural synthons available as N-terminal 'capping' residues for peptide-based drug design. Several novel arginine and lysine analogues stereoselectively modified in the Cα position with a methyl group in place of the α-amine were prepared.