79622-11-0 Usage
Description
m-PEG8-Tos, also known as methoxy-poly(ethylene glycol) with an 8-atom chain length and a tosyl group, is a PEG-based linker that features a tosyl group as a leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer enhances solubility in aqueous media, making it a versatile component in various applications.
Uses
Used in Bioconjugation:
m-PEG8-Tos is used as a bioconjugation agent for attaching biomolecules to other molecules or surfaces. The tosyl group facilitates nucleophilic substitution reactions, allowing for the efficient coupling of the PEG spacer to target molecules.
Used in Drug Delivery Systems:
In the pharmaceutical industry, m-PEG8-Tos is used as a component in drug delivery systems to improve the solubility, stability, and bioavailability of therapeutic agents. The hydrophilic PEG spacer can help reduce the immunogenicity and non-specific interactions of drug molecules, enhancing their therapeutic efficacy.
Used in Polymer Science:
m-PEG8-Tos is utilized as a building block in the synthesis of various polymers and copolymers. The PEG-based structure allows for the creation of materials with tailored properties, such as hydrophilicity, biocompatibility, and self-assembly behavior, which can be applied in areas like hydrogels, micelles, and nanoparticles.
Used in Chemical Synthesis:
In organic synthesis, m-PEG8-Tos serves as a versatile intermediate for the preparation of a wide range of PEGylated compounds. The tosyl group's reactivity in nucleophilic substitution reactions enables the synthesis of various functionalized PEG derivatives for use in research and industry.
Check Digit Verification of cas no
The CAS Registry Mumber 79622-11-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,9,6,2 and 2 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 79622-11:
(7*7)+(6*9)+(5*6)+(4*2)+(3*2)+(2*1)+(1*1)=150
150 % 10 = 0
So 79622-11-0 is a valid CAS Registry Number.
79622-11-0Relevant articles and documents
Synthesis and self-assembly of rod-coil molecules with n-shaped rod building block
Zhong, Ke-Li,Huang, Zhegang,Man, Zhijin,Jin, Long Yi.,Yin, Bingzhu,Lee, Myongsoo
, p. 1415 - 1422 (2010)
The rod-coil molecules with n-shaped rod building block, consisting of an anthracene unit and two biphenyl groups linked together with acetylenyl bonds at the 1,8-position of anthracene as a rigid rod segment, and the alkyl or alkyloxy chains with various
Novel amphiphilic PEO-grafted cardo poly(aryl ether sulfone) copolymer: Synthesis, characterization and antifouling performance
Hou, Shuhua,Zheng, Jifu,Zhang, Suobo,Li, Shenghai
, p. 48 - 54 (2015)
A series of comb-like amphiphilic copolymers (PES-g-PEO) were synthesized through grafting poly(ethylene oxide) (PEO) to cardo poly(aryl ether sulfone) (PES-NH) backbone. By controlling the ratios of PEO and cardo poly(aryl ether sulfone), amphiphilic cop
n-Type Rigid Semiconducting Polymers Bearing Oligo(Ethylene Glycol) Side Chains for High-Performance Organic Electrochemical Transistors
Chen, Xingxing,Marks, Adam,Paulsen, Bryan D.,Wu, Ruiheng,Rashid, Reem B.,Chen, Hu,Alsufyani, Maryam,Rivnay, Jonathan,McCulloch, Iain
, p. 9368 - 9373 (2021/03/16)
N-type conjugated polymers as the semiconducting component of organic electrochemical transistors (OECTs) are still undeveloped with respect to their p-type counterparts. Herein, we report two rigid n-type conjugated polymers bearing oligo(ethylene glycol
AN IMPROVED PROCESS FOR THE PREPARATION OF (5Α,6Α)-17-ALLYL-6-(2,5,8,11,14,17,20- HEPTAOXADOCOSAN-22-YLOXY)-4,5-EPOXYMORPHINAN-3,14-DIOL AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS
-
, (2019/04/16)
The present invention relates to an improved process for the preparation of (5α, 6α)-17-allyl-6-(2, 5, 8, 11, 14, 17, 20- heptaoxadocosan-22-yloxy)-4, 5-epoxymorphinan-3, 14-diol which is represented by the following structural formula-1 or its pharmaceut
