796851-03-1

Basic information

• Product Name: Pyridine, 2,5-dichloro-4-iodo-
• Synonyms: Pyridine, 2,5-dichloro-4-iodo-;2,5-Dichloro-4-iodopyridine
• CAS NO: 796851-03-1
• Molecular Formula: C₅H₂Cl₂IN
• Molecular Weight: 273.89
• Product Categories: Propidium heterocyclic series
• Mol File: 796851-03-1.mol
• Article Data: 7

Chemical Properties

• Melting Point: 140 ºC
• Boiling Point: 279 ºC
• Flash Point: 122 ºC
• Appearance: /
• Density: 2.129
• Refractive Index: 1.652
• Storage Temp.: Refrigerated.
• CAS DataBase Reference: Pyridine, 2,5-dichloro-4-iodo-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyridine, 2,5-dichloro-4-iodo-(796851-03-1)
• EPA Substance Registry System: Pyridine, 2,5-dichloro-4-iodo-(796851-03-1)

Safety Data

• Hazardous Substances Data: 796851-03-1(Hazardous Substances Data)

Usage

General Description

2,5-dichloro-4-iodo-pyridine is an organic chemical compound with the molecular formula C5H2Cl2IN. It is a derivative of pyridine, which is a six-membered heterocyclic ring. This particular compound has chlorine and iodine substituents at the 2,5 positions of the pyridine ring. 2,5-dichloro-4-iodo-pyridine is commonly used as an intermediate in the synthesis of pharmaceuticals, agricultural chemicals, and other fine chemicals. It is also known for its use in organic synthesis and as a building block in chemical reactions. The compound is mainly used in research and development laboratories for its unique reactivity and versatility in organic synthesis.

InChI:InChI=1/C5H2Cl2IN/c6-3-2-9-5(7)1-4(3)8/h1-2H

Upstream product

• 16110-09-1 2,5 dichloropyridine 

Downstream Products

• 89719-92-6 2,5-dichloro-4-(trifluoromethyl)pyridine 
• 1156542-30-1 2-bromo-5-fluoro-4-(trifluoromethyl)pyridine 
• 1201935-46-7 2-[(2,5-dichloropyridin-4-yl)amino]-N-methoxy-N-methylbenzamide 
• 1201935-60-5 2-[(2,5-dichloropyridin-4-yl)amino]-6-fluoro-N-methylbenzamide 
• 1061358-83-5 2-[(2,5-dichloropyridin-4-yl)amino]-N-methylbenzamide 
• 1201935-59-2 2-[(2,5-dichloropyridin-4-yl)amino]-3-fluoro-N-methylbenzamide 
• 1201935-41-2 2-[(2,5-dichloro-4-pyridinyl)amino]-N-(methyloxy)benzamide 
• 1224887-33-5 2-[(2,5-Di chloro-4-pyridinyl)amino]-5-[4-(2-hydroxyethyl)-1-piperazinyl]-N-methylbenzamide 
• 1184931-56-3 2-[(2,5-dichloro-4-pyridinyl)amino]benzoic acid 
• 1224887-80-2 2-[(2,5-dichloro-4-pyridinyl)amino]benzonitrile 
• 1224888-13-4 2-[(5-chloro-2-{[3-methyl-1-(1-methylethyl)-1H-pyrazol-5-yl]amino}-4-pyridinyl)amino]-4-fluorobenzoic acid 
• 1224888-03-2 4-chloro-2-[(2,5-dichloro-4-pyridinyl)amino]benzonitrile 
• 1224888-11-2 2-[(5-chloro-2-{[3-methyl-1-(1-methylethyl)-1H-pyrazol-5-yl]amino}-4-pyridinyl)amino]-3-fluorobenzonitrile 
• 1224888-05-4 5-chloro-2-[(2,5-dichloro-4-pyridinyl)amino]benzonitrile 

Relevant articles and documents

POLYSUBSTITUTED PYRIDINE COMPOUND, PREPARATION METHOD, USE AND PHARMACEUTICAL COMPOSITION

The present invention provides a polysubstituted pyridine compound of Formula I, a preparation method, a use and a pharmaceutical composition thereof. The polysubstituted pyridine compound of Formula I according to the present invention has an excellent anti-tumor effect, can inhibit various cell kinases simultaneously, has significantly excellent pharmacokinetic characteristics, and is very suitable for oral and intravenous administration. The pharmaceutical composition according to the present invention can be useful for treating tumors and cancers.

Deprotonative metalation of chloro- and bromopyridines using amido-based bimetallic species and regioselectivity-computed CH acidity relationships

A series of chloro- and bromopyridines have been deprotometalated by using a range of 2,2,6,6-tetramethylpiperidino-based mixed lithium-metal combinations. Whereas lithium-zinc and lithium-cadmium bases afforded different mono- and diiodides after subsequent interception with iodine, complete regioselectivities were observed with the corresponding lithium-copper combination, as demonstrated by subsequent trapping with benzoyl chlorides. The obtained selectivities have been discussed in light of the CH acidities of the substrates, determined both in the gas phase and as a solution in THF by using the DFT B3LYP method.

PYRIDINE COMPOUND, PESTICIDAL COMPOSITION AND METHOD OF CONTROLLING PEST

A pyridine compound represented by the following general formula (1); the pyridine compound in which R1 is a C1-C3 fluoroalkyl group or a C1-C3 fluoroalkoxy group; the pyridine compound in which R2 is a hydrogen atom; the pyridine compound in which R2 is a group represented by Q1; a pesticidal composition containing the pyridine compound as an active ingredient; and a method of controlling a pest including applying an effective amount of the pyridine compound to the pest or a place where the pest inhabits, are provided.