79772-17-1

Basic information

• Product Name: 5,5-dimethyl-4-oxo-3-(phenylthio)hexanoic acid
• Synonyms: 5,5-dimethyl-4-oxo-3-(phenylthio)hexanoic acid
• CAS NO: 79772-17-1
• Molecular Weight: 266.361
• Mol File: 79772-17-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5,5-dimethyl-4-oxo-3-(phenylthio)hexanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 5,5-dimethyl-4-oxo-3-(phenylthio)hexanoic acid(79772-17-1)
• EPA Substance Registry System: 5,5-dimethyl-4-oxo-3-(phenylthio)hexanoic acid(79772-17-1)

Safety Data

• Hazardous Substances Data: 79772-17-1(Hazardous Substances Data)

Upstream product

• 37471-41-3 3,3-dimethyl-1-(phenylthio)butan-2-one 
• 15973-59-8 potassium iodoacetate 

Downstream Products

• 79749-89-6 4-(phenylthio)-5-t-butyl-4,5-dihydrofuran-2(3H)-one 

Relevant articles and documents

Synthesis of Butenolides from α-(Phenylthio)-ketones and -esters: Crystal Structure of an Intermediate β-Phenylthio-γ-lactone

Alkylation of α-(phenylthio)-ketones or -esters with iodoacetate anion gives 1,4-dicarbonyl compounds which are reduced stereoselectively to β-phenylthio-γ-butyrolactones.Oxidation to sulphoxides and thermolysis provides a general synthesis of β- and γ-substituted Δαβ-butenolides.Treatment of 5,5-dimethyl-4-oxo-3-(phenylthio)-hexanoic acid with NaBH4 gives a single γ-lactone whose PhS and But groups are shown to be cis by X-ray crystal structure determination.