80485-53-6

Basic information

• Product Name: [(1-Bromoethenyl)thio]benzene
• Synonyms: [(1-Bromoethenyl)thio]benzene
• CAS NO: 80485-53-6
• Molecular Formula: C₈H₇BrS
• Molecular Weight: 215
• Mol File: 80485-53-6.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 263℃
• Flash Point: 113℃
• Appearance: /
• Density: 1.47
• CAS DataBase Reference: [(1-Bromoethenyl)thio]benzene(CAS DataBase Reference)
• NIST Chemistry Reference: [(1-Bromoethenyl)thio]benzene(80485-53-6)
• EPA Substance Registry System: [(1-Bromoethenyl)thio]benzene(80485-53-6)

Safety Data

• Hazardous Substances Data: 80485-53-6(Hazardous Substances Data)

Usage

Description

[(1-Bromoethenyl)thio]benzene, with the molecular formula C8H7BrS, is a colorless to pale yellow liquid characterized by a pungent odor. This chemical compound is recognized for its utility in organic synthesis and serves as a crucial intermediate in the production of pharmaceuticals and agrochemicals. Its reactivity and structural properties make it a valuable reagent in the preparation of various organic compounds, including thiophenes and benzothiophenes. However, it is essential to handle [(1-Bromoethenyl)thio]benzene with care due to its classification as a toxic and hazardous substance, necessitating the use of personal protective equipment and proper ventilation.

Uses

Used in Organic Synthesis:
[(1-Bromoethenyl)thio]benzene is used as a reagent in organic synthesis for the preparation of a range of organic compounds. Its unique structure allows for versatile reactions and the formation of various products, making it a valuable component in this field.
Used in Pharmaceutical Production:
As an intermediate, [(1-Bromoethenyl)thio]benzene plays a significant role in the production of pharmaceuticals. Its incorporation into the synthesis process contributes to the development of new drugs and medicines, highlighting its importance in the healthcare industry.
Used in Agrochemical Production:
Similarly, [(1-Bromoethenyl)thio]benzene is utilized as an intermediate in the production of agrochemicals, which are essential for the agricultural industry. Its contribution to the development of these chemicals aids in enhancing crop protection and yield.
Used in Research and Development:
Due to its reactivity and structural properties, [(1-Bromoethenyl)thio]benzene is also employed in research and development settings. Scientists and researchers use this compound to explore new reactions, develop novel compounds, and further our understanding of organic chemistry.
Used in Chemical Education:
In educational settings, particularly in chemistry courses and laboratories, [(1-Bromoethenyl)thio]benzene may be used as a teaching aid to demonstrate various chemical reactions and principles, fostering a deeper understanding of organic chemistry among students.
Used in Chemical Analysis:
[(1-Bromoethenyl)thio]benzene can also be employed in chemical analysis to identify and quantify specific substances in a sample. Its unique properties make it a useful tool for analytical chemists working in various industries.
Used in Chemical Manufacturing:
In the chemical manufacturing industry, [(1-Bromoethenyl)thio]benzene is used as a starting material or intermediate in the production of various chemicals, contributing to the development of new products and technologies.
Used in Environmental Applications:
Although not explicitly mentioned in the provided materials, [(1-Bromoethenyl)thio]benzene's properties may also find applications in environmental chemistry, such as in the development of new methods for pollution control or the remediation of contaminated sites.

Upstream product

• 26910-34-9 α-Bromoethyl phenyl sulfoxide 
• 82632-29-9 (1,2-Dibromo-1-phenylsulfanyl-ethyl)-trimethyl-silane 
• 1822-73-7 phenylthioethylene 

Downstream Products

• 98204-60-5 2-(phenylthio)-1-decene 
• 121213-53-4 C₂₂H₂₆S₂ 
• 109769-49-5 ((E)-4,4-Dimethyl-1-methylene-pent-2-enylsulfanyl)-benzene 
• 121213-61-4 Acetic acid (3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-((R)-1-methyl-3-phenylsulfanyl-but-3-enyl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl ester 
• 127333-83-9 tert-Butyl-dimethyl-(1-methyl-5-phenylsulfanyl-hex-5-enyloxy)-silane 
• 121213-52-3 (4-Methoxymethoxy-1-methylene-decylsulfanyl)-benzene 
• 77202-27-8 3-(phenylthio)-3-buten-2-ol 
• 165403-05-4 (5R,6R)-6-(tert-butyldimethylsiloxy)-2-(phenylthio)-5-<<2-(trimethylsilyl)ethoxy>methoxy>-1-octene 
• 424835-12-1 2-methoxy-5-(3-phenylsulfanyl-but-3-enyl)-tetrahydro-furan 
• 424835-14-3 2-methoxy-7-(3-phenylsulfanyl-but-3-enyl)-oxepane 
• 424835-15-4 2-methoxy-7-(1-methyl-3-phenylsulfanyl-but-3-enyl)-oxepane 
• 494211-85-7 methyl 5,6,8-trideoxy-2,3-O-(1-methylethylidene)-7-S-phenyl-7-thio-β-D-ribo-oct-7-enofuranoside 
• 494211-87-9 (2R,3S,5S)-3-(benzyloxy)-5-methoxy-2-[3-(phenylthio)but-3-enyl]tetrahydrofuran 
• 494211-90-4 (2R,3S,5S)-3-(benzyloxy)-5-methoxy-2-[4-(phenylthio)pent-4-enyl]tetrahydrofuran 

Relevant articles and documents

Palladium(0)-catalyzed reaction of 9-alkyl-9-borabicyclo[3.3.1]nonane with 1-bromo-1-phenylthioethene: 4-(3-Cyclohexenyl)-2-phenylthio-1-butene

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Reactions of 3-(Phenylthio)-3-buten-2-one with Cycloalkanones. A New Approach to Fused Phenols

Synthesis and properties of 3-(phenylthio)-3-buten-2-one (7) have been described.The butenone 7 reacted with lithium cycloalkanone enolates to give ketols 14 or diketones 15 in good yields, which were easily transformed into fused phenols 17 by the treatment with p-toluenesulfonic acid or sodium ethoxide, respectively.Oxidative elimination of the sulfenyl group of 14a afforded also 2-naphthol 17a.Tetrahydronaphthalene 23, a key intermediate of calamenene 1a and calamenenal 1b, was successfully synthesized by this approach by starting from l-carvone (19).Bicyclooctanone 25 was obtained in the reaction of 7 with kinetic enolate of 2-cyclohexen-1-one in 84percent yield.