80563-86-6

Basic information

• Product Name: 3-CHLORO-2-METHYLBENZENESULFONYL CHLORIDE
• Synonyms: BUTTPARK 37\11-61;3-CHLORO-2-METHYLBENZENE-1-SULFONYL CHLORIDE;3-CHLORO-2-METHYLBENZENESULFONYL CHLORIDE;3-CHLORO-2-METHYLBENZENESULPHONYL CHLORIDE;3-Chloro-o-toluenesulphonyl chloride;3-CHLORO-2-METHYLBENZENESULFONYL CHLORID;Benzenesulfonyl chloride, 3-chloro-2-methyl- (9CI);3-Chloro-o-toluenesulfonylchloride
• CAS NO: 80563-86-6
• Molecular Formula: C₇H₆Cl₂O₂S
• Molecular Weight: 225.09
• Product Categories: SULFONYLHALIDE;Benzenesulfonyl chloride;Organic Building Blocks;Sulfonyl Halides;Sulfur Compounds
• Mol File: 80563-86-6.mol
• Article Data: 1

Chemical Properties

• Melting Point: 71-74 °C(lit.)
• Boiling Point: 312.6 °C at 760 mmHg
• Flash Point: 142.9 °C
• Appearance: White to light yellow/Crystals
• Density: 1.458 g/cm³
• Vapor Pressure: 0.000963mmHg at 25°C
• Refractive Index: 1.559
• Storage Temp.: Inert atmosphere,Room Temperature
• Sensitive: Moisture Sensitive
• BRN: 3261529
• CAS DataBase Reference: 3-CHLORO-2-METHYLBENZENESULFONYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-CHLORO-2-METHYLBENZENESULFONYL CHLORIDE(80563-86-6)
• EPA Substance Registry System: 3-CHLORO-2-METHYLBENZENESULFONYL CHLORIDE(80563-86-6)

Safety Data

• Hazard Codes: C,Xi
• Statements: 34
• Safety Statements: 26-36/37/39-45-39-37-36
• RIDADR: UN 3261 8/PG 2
• WGK Germany: 3
• HazardClass: 8
• PackingGroup: II
• Hazardous Substances Data: 80563-86-6(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 80563-86-6 differently. You can refer to the following data:
1. 3-Chloro-2-methylbenzenesulfonyl Chloride is used in preparation of benzisoxazole sulfonamides useful in treatment of diseases.
2. 3-Chloro-2-methylbenzenesulfonyl chloride may be used in the synthesis of ethyl [6-(3-chloro-2-methyl-benzenesulfonyl-amino)-pyridin-2-yl]-acetate and ethyl 2-(2-{[(3-chloro-2-methylphenyl)sulfonyl]amino}-1,3-thiazol-4-yl)acetate.

General Description

3-Chloro-2-methylbenzenesulfonyl chloride is an aryl sulfonyl chloride derivative.

InChI:InChI=1/C7H6Cl2O2S/c1-5-6(8)3-2-4-7(5)12(9,10)11/h2-4H,1H3

Upstream product

• 133-59-5 Toluene-2-sulfonyl chloride 
• 87-60-5 3-chloro-2-methylbenzenamine 

Downstream Products

• 3476-01-5 2-chloro-6-sulfotoluene 
• 95-49-8 2-methylchlorobenzene 
• 345954-54-3 1-[2-(3-Chloro-2-methyl-benzenesulfonylamino)-acetyl]-piperidine-4-carboxylic acid ethyl ester 
• 375844-31-8 ethyl 2-(2-{[(3-chloro-2-methylphenyl)sulfonyl]amino}-1,3-thiazol-4-yl)acetate 

Relevant articles and documents

4-Hydroxy-1,2-Benzisothiazol-3(2H)-one-1,1-dioxides and salts thereof

Compounds of the formula STR1 wherein R1 is hydrogen or hydroxyl, and non-toxic, pharmacologically acceptable salts thereof formed with inorganic or organic bases. The compounds as well as their salts are useful as sweetening agents.