80999-72-0

Basic information

• Product Name: 1H-Purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-8-[(phenylamino)methyl]-
• CAS NO: 80999-72-0
• Molecular Formula: C14H15N5O2
• Molecular Weight: 285.305
• Mol File: 80999-72-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1H-Purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-8-[(phenylamino)methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-8-[(phenylamino)methyl]-(80999-72-0)
• EPA Substance Registry System: 1H-Purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-8-[(phenylamino)methyl]-(80999-72-0)

Safety Data

• Hazardous Substances Data: 80999-72-0(Hazardous Substances Data)

Upstream product

• 64398-14-7 8-chloromethyltheophylline 
• 62-53-3 aniline 
• 122707-25-9 6-amino-1,3-dimethyl-5-phenylazouracilate 
• 2879-16-5 8-hydroxymethyltheophylline 
• 80999-66-2 1,3-dimethyl-6-ethoxycarbonylvinylamino-5-phenylazouracil 

Relevant articles and documents

A Novel Synthesis of Theophylline Derivatives

Treatment of 6-amino-5-arylazo-1,3-dimethyluracils with ethyl propiolate gave the corresponding Michael-type adducts, 5-arylazo-1,3-dimethyl-6-ethoxycarbonylvinylaminouracils, which on treatment with a mixture of hydrochloric acid and acetic acid caused the acid-catalyzed rearrangement accompanied with rearrangement to give rise to the corresponding 8-anilinomethyltheophylline derivatives.In the case that the arylazo group possesses an electron-releasing substituent such as methoxy, the reaction proceeded ina different way to afford 1,2-bis(theophyllin-8-yl)ethane.The presumable reaction mechanisms for the above purine syntheses were proposed.