64398-14-7

Basic information

• Product Name: 8-(chloromethyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione
• Synonyms: 1H-Purine-2,6-dione, 8-(chloromethyl)-3,7-dihydro-1,3-dimethyl-
• CAS NO: 64398-14-7
• Molecular Formula: C₈H₉ClN₄O₂
• Molecular Weight: 228.6357
• Mol File: 64398-14-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 490.5°C at 760 mmHg
• Flash Point: 250.4°C
• Density: 1.518g/cm³
• Vapor Pressure: 9.11E-10mmHg at 25°C
• Refractive Index: 1.62
• CAS DataBase Reference: 8-(chloromethyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 8-(chloromethyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione(64398-14-7)
• EPA Substance Registry System: 8-(chloromethyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione(64398-14-7)

Safety Data

• Hazardous Substances Data: 64398-14-7(Hazardous Substances Data)

Upstream product

• 2879-16-5 8-hydroxymethyltheophylline 

Downstream Products

• 109642-95-7 8-[(cyclohexyl-methyl-amino)-methyl]-1,3-dimethyl-3,7-dihydro-purine-2,6-dione 
• 109437-46-9 8-(cyclohexylamino-methyl)-1,3-dimethyl-3,7-dihydro-purine-2,6-dione 
• 116567-96-5 1,3,1',3'-tetramethyl-3,7,3',7'-tetrahydro-8,8'-(2-cyclohexyl-2-aza-propane-1,3-diyl)-bis-purine-2,6-dione 
• 133231-18-2 8-[(N-ethyl-anilino)-methyl]-1,3-dimethyl-3,7-dihydro-purine-2,6-dione 
• 80999-75-3 8-[(3,4-Dimethyl-phenylamino)-methyl]-1,3-dimethyl-3,7-dihydro-purine-2,6-dione 
• 80999-72-0 8-anilinomethyltheophylline 
• 108-74-7 1,3,5-trimethyl-1,3,5-triazacyclohexane 
• 127855-49-6 1,3,6,8-Tetramethyl-6,7,8,9-tetrahydro-1H,5H-1,3,4b,6,8,10-hexaaza-benzo[a]azulene-2,4-dione 
• 100086-67-7 8-[(N-benzyl-anilino)-methyl]-1,3-dimethyl-3,7-dihydro-purine-2,6-dione 

Relevant articles and documents

A Novel Synthesis of Theophylline Derivatives

Treatment of 6-amino-5-arylazo-1,3-dimethyluracils with ethyl propiolate gave the corresponding Michael-type adducts, 5-arylazo-1,3-dimethyl-6-ethoxycarbonylvinylaminouracils, which on treatment with a mixture of hydrochloric acid and acetic acid caused the acid-catalyzed rearrangement accompanied with rearrangement to give rise to the corresponding 8-anilinomethyltheophylline derivatives.In the case that the arylazo group possesses an electron-releasing substituent such as methoxy, the reaction proceeded ina different way to afford 1,2-bis(theophyllin-8-yl)ethane.The presumable reaction mechanisms for the above purine syntheses were proposed.