80999-75-3

Basic information

• Product Name: 8-[(3,4-Dimethyl-phenylamino)-methyl]-1,3-dimethyl-3,7-dihydro-purine-2,6-dione
• Synonyms: 8-[(3,4-Dimethyl-phenylamino)-methyl]-1,3-dimethyl-3,7-dihydro-purine-2,6-dione
• CAS NO: 80999-75-3
• Molecular Weight: 313.359
• Mol File: 80999-75-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 8-[(3,4-Dimethyl-phenylamino)-methyl]-1,3-dimethyl-3,7-dihydro-purine-2,6-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 8-[(3,4-Dimethyl-phenylamino)-methyl]-1,3-dimethyl-3,7-dihydro-purine-2,6-dione(80999-75-3)
• EPA Substance Registry System: 8-[(3,4-Dimethyl-phenylamino)-methyl]-1,3-dimethyl-3,7-dihydro-purine-2,6-dione(80999-75-3)

Safety Data

• Hazardous Substances Data: 80999-75-3(Hazardous Substances Data)

Upstream product

• 68321-58-4 6-Amino-5-(3,4-dimethyl-phenylazo)-1,3-dimethyl-1H-pyrimidine-2,4-dione 
• 2879-16-5 8-hydroxymethyltheophylline 
• 80999-71-9 (Z)-3-[5-(3,4-Dimethyl-phenylazo)-1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-pyrimidin-4-ylamino]-acrylic acid ethyl ester 
• 64398-14-7 8-chloromethyltheophylline 
• 95-64-7 4-amino-o-xylene 

Relevant articles and documents

A Novel Synthesis of Theophylline Derivatives

Treatment of 6-amino-5-arylazo-1,3-dimethyluracils with ethyl propiolate gave the corresponding Michael-type adducts, 5-arylazo-1,3-dimethyl-6-ethoxycarbonylvinylaminouracils, which on treatment with a mixture of hydrochloric acid and acetic acid caused the acid-catalyzed rearrangement accompanied with rearrangement to give rise to the corresponding 8-anilinomethyltheophylline derivatives.In the case that the arylazo group possesses an electron-releasing substituent such as methoxy, the reaction proceeded ina different way to afford 1,2-bis(theophyllin-8-yl)ethane.The presumable reaction mechanisms for the above purine syntheses were proposed.