81012-82-0

Basic information

• Product Name: (2-bromobutyl)benzene
• Synonyms: (2-Bromobutyl)benzene; Benzene, (2-bromobutyl)-
• CAS NO: 81012-82-0
• Molecular Formula: C₁₀H₁₃Br
• Molecular Weight: 213.1142
• Mol File: 81012-82-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 235.9°C at 760 mmHg
• Flash Point: 104.9°C
• Density: 1.262g/cm³
• Vapor Pressure: 0.0747mmHg at 25°C
• Refractive Index: 1.537
• CAS DataBase Reference: (2-bromobutyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: (2-bromobutyl)benzene(81012-82-0)
• EPA Substance Registry System: (2-bromobutyl)benzene(81012-82-0)

Safety Data

• Hazardous Substances Data: 81012-82-0(Hazardous Substances Data)

Usage

General Description

(2-bromobutyl)benzene is a chemical compound commonly used as a benzene derivative in organic synthesis. It is formed by the reaction between 2-bromobutane and benzene, and it is frequently used as an intermediate in the production of pharmaceuticals and other fine chemicals. It is a colorless to pale yellow liquid with a faint odor and is insoluble in water. (2-bromobutyl)benzene is known to be hazardous if inhaled or swallowed, and it should be handled with care in a well-ventilated area and protective gear. It is also a regulated chemical due to its potential environmental and health impacts.

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Relevant articles and documents

Synthesis of Alkyl Halides from Aldehydes via Deformylative Halogenation

An unprecedented deformylative halogenation of aldehydes to alkyl halides is presented. Under oxidative conditions, 1,4-dihydropyridine (DHP), derived from an aldehyde, generated a C(sp3)- radical that coupled with a halogen radical that was generated from inexpensive and atom-economical halogen sources (NaBr, NaI, or HCl), to yield an alkyl halide. Because of the mild conditions, a wide range of functional groups were tolerated, and excellent site selectivity was achieved.

Visible-light-mediated conversion of alcohols to halides

The development of new means of activating molecules and bonds for chemical reactions is a fundamental objective for chemists. In this regard, visible-light photoredox catalysis has emerged as a powerful technique for chemoselective activation of chemical bonds under mild reaction conditions. Here, we report a visible-light-mediated photocatalytic alcohol activation, which we use to convert alcohols to the corresponding bromides and iodides in good yields, with exceptional functional group tolerance. In this fundamentally useful reaction, the design and operation of the process is simple, the reaction is highly efficient, and the formation of stoichiometric waste products is minimized.