81018-77-1Relevant articles and documents
A further step to sustainable palladium catalyzed oxidation: Allylic oxidation of alkenes in green solvents
dos Santos Costa, Maíra,de Camargo Faria, Amanda,Mota, Rayssa L.V.,Gusevskaya, Elena V.
, (2021/09/14)
The palladium catalyzed oxidation of alkenes with molecular oxygen is a synthetically important reaction which employs palladium catalysts in solution; therefore, a solvent plays a critical role for the process. In this study, we have tested several green solvents as a reaction medium for the allylic oxidation of a series of alkenes. Dimethylcarbonate, methyl isobutyl ketone, and propylene carbonate, solvents with impressive sustainability ranks and very scarcely exploited in palladium catalyzed oxidations, were proved to be excellent alternatives for the solvents conventionally employed in these processes, such as acetic acid. Palladium acetate alone or in the combination with p-benzoquinone efficiently operates as the catalyst for the oxidation of alkenes by dioxygen under 5–10 atm. For most substrates, the systems in green solvents showed better selectivity for allylic oxidation products as compared to pure acetic acid; moreover, the reactions in propylene carbonate solutions occurred even faster than in acetic acid.
A new biomimetic-like aromatization of the cyclic end groups of terpenoids with stereospecific migration of one of the methyl groups: A convenient route to isorenieratene (φ,φ-carotene)
Valla, Alain,Andriamialisoa, Zo,Valla, Benoist,Labia, Roger,Le Guillou, Regis,Dufosse, Laurent,Cartier, Dominique
, p. 711 - 715 (2007/10/03)
The synthesis of isorenieratene, a natural carotenoid isolated from the marine sponge Reniera japonica and from some anoxygenic phototrophic bacteria or nonphotosynthetic actinomycetes, was performed from α-, β- and retro-ionones. In this series of cycloh
A new synthesis of 4-(2,3,6-trimethylphenyl)butan-2-ol, a C13-norisoprenoid artifact from Vitis vinifera linn. and its conversion to several terpenic natural products of plant and marine origin
Sudalai, A.,Rao, Krishna G. S.
, p. 110 - 112 (2007/10/02)
The four-step synthesis of 4-(2,3,6-trimethylphenyl)butan-2-ol (1), starts from 5,8-dimethyl-3,4-dihydro-2-naphthaldehyde (2).The trimethyldihydronaphthalene (10) obtained from the reduction of 2 is ozonised to the keto aldehyde (11), which is reduced to