81265-90-9 Usage
Chemical class
Indazole cannabinoids
Receptor
CB1 (cannabinoid receptor)
Function
Potent and selective agonist
Affinity
High affinity for the CB1 receptor
Effects
Strong binding and activation of the CB1 receptor
Applications
Research chemical for studying CB1 receptor activation, potential use in pharmaceutical drugs for pain management and neurological disorders
Legal status
Controlled substance in many countries with legal restrictions due to psychoactive properties.
Check Digit Verification of cas no
The CAS Registry Mumber 81265-90-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,1,2,6 and 5 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 81265-90:
(7*8)+(6*1)+(5*2)+(4*6)+(3*5)+(2*9)+(1*0)=129
129 % 10 = 9
So 81265-90-9 is a valid CAS Registry Number.
81265-90-9Relevant articles and documents
Room-Temperature, Metal-Free, and One-Pot Preparation of 2H-Indazoles through a Mills Reaction and Cyclization Sequence
Kondo, Masaru,Takizawa, Shinobu,Jiang, Yuzhao,Sasai, Hiroaki
, p. 9866 - 9869 (2019)
The Mills reaction and cyclization of readily available 2-aminobenzyl alcohols and nitrosobenzenes using thionyl bromide provided 2H-indazoles in up to 88 % yields. In the metal-free process, acetic acid played a crucial role for the both Mills reaction and cyclization. A brominated 2H-indazole could also be obtained through the one-pot sequence.
