81569-58-6

Basic information

• Product Name: 5-Thiazolecarboxylicacid,2-bromo-4-(1-methylethyl)-,ethylester(9CI)
• Synonyms: 5-Thiazolecarboxylicacid,2-bromo-4-(1-methylethyl)-,ethylester(9CI);Ethyl 2-bromo-4-isopropylthiazole-5-carboxylate
• CAS NO: 81569-58-6
• Molecular Formula: C₉H₁₂BrNO₂S
• Molecular Weight: 278.17
• Product Categories: THIAZOLE
• Mol File: 81569-58-6.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 5-Thiazolecarboxylicacid,2-bromo-4-(1-methylethyl)-,ethylester(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Thiazolecarboxylicacid,2-bromo-4-(1-methylethyl)-,ethylester(9CI)(81569-58-6)
• EPA Substance Registry System: 5-Thiazolecarboxylicacid,2-bromo-4-(1-methylethyl)-,ethylester(9CI)(81569-58-6)

Safety Data

• Hazardous Substances Data: 81569-58-6(Hazardous Substances Data)

Upstream product

• 72850-76-1 ethyl 2-amino-4-isopropyl-1,3-thiazole-5-carboxylate 
• 81569-67-7 2-bromo-4-methyl-3-oxo-pentanoic acid ethyl ester 
• 7152-15-0 ethyl 4-methyl-3-oxo-pentanoate 

Downstream Products

• 1610853-10-5 4-isopropyl-2-(methyl-tetrahydro-pyran-4-yl-amino)-N-[1-[3-(trifluoromethyloxy)-phenyl]-ethyl]-thiazole-5-carboxylic acid amide 

Relevant articles and documents

SUBSTITUTED AMINO-ACRYLCARBOXAMIDES AS KCNQ2/3 MODULATORS

The invention relates to amino-arylcarboxamides, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.

IMIDAZOLE CARBONYL COMPOUND

To develop an antibiotic having a novel mechanism of action, the present inventors have searched for a compound that has weak cytotoxicity, the physical property of high solubility in water, the effect of inhibiting both DNA gyrase GyrB and topoisomerase IV ParE subunits, and sufficient antibacterial activity. As a result, the present inventors have completed the present invention by finding that a compound of the present invention represented by the general formula (1), a pharmacologically acceptable salt thereof, and a prodrug thereof have desirable properties. The present invention provides a pharmaceutical composition (particularly, a preventive or therapeutic composition for infectious disease) comprising a compound represented by the formula (1), a pharmacologically acceptable salt thereof, or a prodrug thereof as an active ingredient.

Benzofuran and dihydrobenzofuran derivatives useful as beta-3 adrenoreceptor agonists

This invention relates to novel benzofuran and dihydrobenzofuran compounds, pharmaceutical compositions containing such compounds, and methods of treating beta-3 adrenoreceptor-mediated conditions with such compositions.