81794-13-0 Usage
General Description
2'-O-tert-Butyldimethylsilyl-5'-O-DMT-adenosine is a chemical compound that is commonly used in organic synthesis. It is a modified form of adenosine, a nucleoside that is a building block for RNA. 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-adenosine is often used in the production of RNA molecules for research and biotechnological applications. The tert-butyldimethylsilyl (TBDMS) group on the 2'-O position and the 5'-O-dimethoxytrityl (DMT) group on the 5'-O position protect the adenosine molecule, allowing for selective deprotection and further manipulation of the compound in chemical reactions. Its unique structure and reactivity make 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-adenosine an important tool in the field of nucleic acid chemistry and molecular biology.
Check Digit Verification of cas no
The CAS Registry Mumber 81794-13-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,1,7,9 and 4 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 81794-13:
(7*8)+(6*1)+(5*7)+(4*9)+(3*4)+(2*1)+(1*3)=150
150 % 10 = 0
So 81794-13-0 is a valid CAS Registry Number.
81794-13-0Relevant articles and documents
Preparation of deoxynucleosides
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Page column 16-17, (2008/06/13)
Methods for preparing deoxynucleosides from their corresponding ribonucleosides by forming 3-tert-butylphenoxythiocarbonylderivatives of the ribonucleosides and subsequently effecting radical deoxygenation reactions at the carbon atoms to be deoxygenated.
HIGH YIELD SELECTIVE 3'-SILYLATION OF RIBONUCLEOSIDES
Hakimelahi, Gholam H.,Proba, Zbigniew A.,Ogilvie, Kelvin K.
, p. 5243 - 5246 (2007/10/02)
Prucedures have been developed which permit the highly selective silylation of the 3'-hydroxyl of ribonucleosides to produce 3',5'-diprotected derivatives in high yields.
