81852-81-5

Basic information

• Product Name: 1H-Pyrrole,1-methyl-2-(1-methylethenyl)-(9CI)
• Synonyms: 1H-Pyrrole,1-methyl-2-(1-methylethenyl)-(9CI)
• CAS NO: 81852-81-5
• Molecular Formula: C₈H₁₁N
• Molecular Weight: 121.17964
• Product Categories: AMINETERTIARY
• Mol File: 81852-81-5.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-Pyrrole,1-methyl-2-(1-methylethenyl)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrole,1-methyl-2-(1-methylethenyl)-(9CI)(81852-81-5)
• EPA Substance Registry System: 1H-Pyrrole,1-methyl-2-(1-methylethenyl)-(9CI)(81852-81-5)

Safety Data

• Hazardous Substances Data: 81852-81-5(Hazardous Substances Data)

Upstream product

• 81852-76-8 2-(1-Methyl-2-pyrrolyl)-2-propanol 
• 31785-72-5 1-methyl-2-pyrrolyllithium 
• 932-16-1 N-methyl-2-acetylpyrrole 
• 1779-49-3 Methyltriphenylphosphonium bromide 

Downstream Products

• 1206552-60-4 (+)-(R)-2-(2-methoxy-1-phenylethyl)-5,6-dimethyl-2H,6H-pyrrolo[3,4-e]indole-1,3-dione 

Relevant articles and documents

Access to indoles via Diels-Alder reactions of 2-vinylpyrroles with maleimides

(Chemical Equation Presented) Variously substituted 2-vinylpyrroles underwent an endo-addition [4+2] cycloaddition reaction with maleimides followed by a spontaneous highly diastereoselective (93-98% de) isomerization to give tetrahydroindoles in moderate to excellent yield. Treatment with activated MnO2 in refluxing toluene provided the corresponding indoles in moderate to good yield. This highly convergent methodology for formation of indoles is versatile and the starting materials are conveniently prepared.