82278-19-1

Basic information

• Product Name: C₁₀H₁₀ClFO
• Synonyms: C₁₀H₁₀ClFO
• CAS NO: 82278-19-1
• Molecular Weight: 200.64
• Mol File: 82278-19-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₁₀H₁₀ClFO(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₀H₁₀ClFO(82278-19-1)
• EPA Substance Registry System: C₁₀H₁₀ClFO(82278-19-1)

Safety Data

• Hazardous Substances Data: 82278-19-1(Hazardous Substances Data)

Upstream product

• 1035261-07-4 ethyl 2-(4-fluorophenyl)-2-methylpropanoate 
• 93748-19-7 2-(4-fluorophenyl)-2-methylpropanoic acid 

Downstream Products

• 1035261-08-5 diethyl 2-(2-(4-fluorophenyl)-2-methylpropanoyl)malonate 

Relevant articles and documents

Palladium(II)-catalyzed directed trifluoromethylthiolation of unactivated C(sp3)-H bonds

The synthesis of trifluoromethylthiolated aliphatic acid derivatives by Pd-catalyzed C(sp3)-H bond functionalization was developed. Using a bidentate directing group, the direct and selective introduction of a SCF3 moiety was possible on a range of amides with remarkable selectivity for C(sp3)-centers with an electrophilic SCF3 source and pivalic acid as an additive. This work constitutes an example of the unactivated C(sp3)-SCF3 bond formation by C-H activation offering a new access to relevant molecules.