82543-07-5

Basic information

• Product Name: 3H-Cycloprop[15,16]androsta-5,15-dien-17-one,15,16-dihydro-3,7-dihydroxy-,
• Synonyms: 3H-Cycloprop[15,16]androsta-5,15-dien-17-one,15,16-dihydro-3,7-dihydroxy-,
• CAS NO: 82543-07-5
• Molecular Formula: C₂₀H₂₈O₃
• Molecular Weight: 0
• Product Categories: STEROID
• Mol File: 82543-07-5.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3H-Cycloprop[15,16]androsta-5,15-dien-17-one,15,16-dihydro-3,7-dihydroxy-,(CAS DataBase Reference)
• NIST Chemistry Reference: 3H-Cycloprop[15,16]androsta-5,15-dien-17-one,15,16-dihydro-3,7-dihydroxy-,(82543-07-5)
• EPA Substance Registry System: 3H-Cycloprop[15,16]androsta-5,15-dien-17-one,15,16-dihydro-3,7-dihydroxy-,(82543-07-5)

Safety Data

• Hazardous Substances Data: 82543-07-5(Hazardous Substances Data)

Upstream product

• 67372-65-0 3β-hydorxy-15β,16β-methylene androst-5-ene-17-one 

Downstream Products

• 82543-09-7 7β-hydroxy-15β,16β-methylene-3β-pivaloyloxy-5-androsten-17-one 
• 90457-65-1 dihydrospirorenone 
• 82543-16-6 (2S,4aR,4bS,6aS,7aS,8aS,8bS,8cR,8dR,9aR,9bR)-2,9b-dihydroxy-4a,6a-dimethyloctadecahydro-7H-cyclopropa[4,5]cyclopenta[1,2-a]cyclopropa[l]phenanthren-7-one 
• 82543-17-7 17α-(3-hydroxy-1-propinyl)-6β,7β;15β,16β-dimethylene-5β-androstane-3β,5,17β-triol 
• 74220-07-8 Spirorenone 
• 82543-10-0 3β-(tert.-butyldimethylsilyloxy)-7β-hydroxy-15β,16β-methylene-5-androsten-17-one 
• 82543-12-2 3β-tribenzylsilyloxy-7β-hydroxy-15β,16β-methylene-5-androsten-17-one 

Relevant articles and documents

Steroid hydroxylations with Botryodiplodia malorum and Colletotrichum lini

An improved procedure for the microbial hydroxylations of dehydroepiandrosterone (DHEA, 1) and 15β,16β-methylene-dehydroepiandrosterone (2) was studied using whole cells of Botryodiplodia malorum and Colletotrichum lini. C. lini catalyzed 7α- and 15α-hydroxylation of 1 and 7α-hydroxylation of 2, while B. malorum gave 7β-hydroxylation of both the substrates. The stability of the enzymatic activity was higher in the presence of co-substrates (i.e., glucose or mannitol) allowing for repeated batches of the biotransformations. The yields of 7α,15α-dihydroxy-1 production were improved obtaining 5.8 g l-1 (recovered product) from 7.0 g l-1 of substrate. The structures of the hydroxylated products were assigned by a combination of two-dimensional NMR proton-proton and proton-carbon correlation techniques.