82583-95-7

Basic information

• Product Name: 2-Amino-5-methoxy-4-(phenylmethoxy)benzaldehyde
• Synonyms: 2-Amino-5-methoxy-4-(phenylmethoxy)benzaldehyde;2-aMino-4-(benzyloxy)-5-Methoxybenzaldehyde
• CAS NO: 82583-95-7
• Molecular Formula: C₁₅H₁₅NO₃
• Molecular Weight: 257.288
• Mol File: 82583-95-7.mol
• Article Data: 3

Chemical Properties

• Melting Point: 198-200℃
• Boiling Point: 447.614 °C at 760 mmHg
• Flash Point: 216.37 °C
• Appearance: /
• Density: 1.213
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.626
• CAS DataBase Reference: 2-Amino-5-methoxy-4-(phenylmethoxy)benzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Amino-5-methoxy-4-(phenylmethoxy)benzaldehyde(82583-95-7)
• EPA Substance Registry System: 2-Amino-5-methoxy-4-(phenylmethoxy)benzaldehyde(82583-95-7)

Safety Data

• Hazardous Substances Data: 82583-95-7(Hazardous Substances Data)

Usage

General Description

2-Amino-5-methoxy-4-(phenylmethoxy)benzaldehyde is a complex chemical compound with a specific molecular structure that is comprised of a benzaldehyde group, a methoxy group, a phenylmethoxy group, and an amino group. The presence of the amino group suggests that this compound may have basic properties. 2-Amino-5-methoxy-4-(phenylmethoxy)benzaldehyde, like others in its category, is likely to be utilized in a variety of scientific research and industrial applications, potentially including the pharmaceutical industry for drug synthesis, or as an intermediate in producing other specialized chemicals. However, specific information about this compound is not widely available, indicating that it may not be widely produced or utilized. The properties, uses, and safety measures for this compound would be defined by its detailed Material Safety Data Sheet (MSDS).

InChI:InChI=1/C15H15NO3/c1-18-15-8-11(9-17)14(16)7-12(15)10-19-13-5-3-2-4-6-13/h2-9H,10,16H2,1H3

Upstream product

• 2426-84-8 4-(benzyloxy)-5-methoxy-2-nitrobenzaldehyde 
• 2454-72-0 6-nitrovanillin 
• 712-97-0 6-nitro-1,3-benzodioxole-5-carbaldehyde 
• 82583-99-1 4-Benzyloxy-5-hydroxy-2-nitro-benzaldehyde 
• 20194-18-7 sodium phenyl-methanolate 

Downstream Products

• 40705-22-4 4-benzyloxy-6-bromo-3-methoxybenzaldehyde 

Relevant articles and documents

Synthesis and in-vitro anti-hepatitis-B virus activity of 6H-[1]benzothiopyrano[4,3-b] quinolin-10-ols

A series of 9-methoxy-6H-[1]benzothiopyrano[4,3-b]quinolin-10-ols with a Mannich side chain were synthesized and evaluated for their anti-Hepatitis B virus (HBV) activity in HepG2.2.15 cells. Some compounds showed significant anti-HBV activity with IC50 values less than 41 μM. Among them, compound 9b was the most effective anti-HBV agent (IC50 = 1.7 μM, SI = 60.3).

Cleavage of the Methylenedioxy Ring. III. Cleavage with Sodium Benzyloxide in Dimethyl Sulfoxide

Cleavage of the methylenedioxy ring in aromatic formyl (1-3), nitro (4 and 5), and acetyl (30) compounds with N-sodium benzyloxide-benzyl alcohol in dimethyl sulfoxide gave 3-hydroxybenzene derivatives (19, 22-24, 26, 27, and 33).In the case of the acetyl compound 30, the 4-hydroxybenzene derivative (34) was also obtained as a minor product.Regioselective cleavage of the ring in aromatic compounds having electronwithdrawing groups with nucleophilic oxide anions is discussed.Cleavage of the ring in 1-5 and 30 with 2 N sodium methoxide in dimethyl sulfoxide-dimethylformamide was found to be useful for the practical preparation of 3-hydroxybenzene derivatives (6-10 and 31).Keywords - Cleavage of methylenedioxy ring; regioselectivity; piperonals; 3,4-methylenedioxy-nitrobenzene; 3,4-methylenedioxy-acetophenone; sodium methoxide; sodium phenoxide; sodium benzyloxide; dimethyl sulfoxide; dimethylformamide