2454-72-0 Usage
Description
4-Hydroxy-5-methoxy-2-nitrobenzaldehyde is an organic compound characterized by its molecular structure featuring a nitro group, hydroxyl, and methoxy groups attached to a benzene ring. It is a versatile chemical intermediate with potential applications in various industries due to its unique functional groups.
Uses
Used in Pharmaceutical Industry:
4-Hydroxy-5-methoxy-2-nitrobenzaldehyde is used as a chemical intermediate for the synthesis of pyrrolobenzodiazepines, which are a class of compounds with potential applications in the development of anti-cancer drugs. These compounds have shown to inhibit DNA synthesis and have been studied for their potential use in treating various types of cancer.
Used in Biotechnology Industry:
In the biotechnology field, 4-hydroxy-5-methoxy-2-nitrobenzaldehyde is utilized in the preparation of antibody conjugates. These conjugates are essential for various diagnostic and therapeutic applications, such as targeted drug delivery and imaging techniques. The compound's functional groups allow for the attachment of antibodies to other molecules, enhancing their specificity and effectiveness in biological systems.
Check Digit Verification of cas no
The CAS Registry Mumber 2454-72-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,4,5 and 4 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 2454-72:
(6*2)+(5*4)+(4*5)+(3*4)+(2*7)+(1*2)=80
80 % 10 = 0
So 2454-72-0 is a valid CAS Registry Number.
InChI:InChI=1/C8H7NO5/c1-14-8-2-5(4-10)6(9(12)13)3-7(8)11/h2-4,11H,1H3
2454-72-0Relevant articles and documents
Cleavage of the methylenedioxy group with sodium methoxide in dimethyl sulfoxide
Kobayashi,Kihara,Yamahara
, p. 3113 - 3116 (1978)
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POLYCYCLIC AMIDES AS CYTOTOXIC AGENTS
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, (2020/03/29)
The invention relates to a compound of formula (I): or pharmaceutically acceptable salts, solvates, tautomers, stereoisomers or mixtures thereof; wherein the fused ring moiety is a non-alkylating moiety; and wherein the compounds are useful as medicaments, in particular for use as a drug in an antibody-drug conjugate and in the treatment of a proliferative disease, a bacterial infection, a malarial infection and inflammation.
G-A CROSSLINKING CYTOTOXIC AGENTS
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, (2020/08/22)
The invention relates to a compound of formula (I): or salts, solvates, isomers or tautomers thereof, wherein; A is a group selected from: R1 is selected from H and halogen; either R2 is selected from -CH2-halogen, C1
