82756-11-4

Basic information

• Product Name: 3-Pyridinecarbonitrile, 2-[(4-methoxyphenyl)amino]-6-methyl-
• CAS NO: 82756-11-4
• Molecular Formula: C14H13N3O
• Molecular Weight: 239.277
• Mol File: 82756-11-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-Pyridinecarbonitrile, 2-[(4-methoxyphenyl)amino]-6-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyridinecarbonitrile, 2-[(4-methoxyphenyl)amino]-6-methyl-(82756-11-4)
• EPA Substance Registry System: 3-Pyridinecarbonitrile, 2-[(4-methoxyphenyl)amino]-6-methyl-(82756-11-4)

Safety Data

• Hazardous Substances Data: 82756-11-4(Hazardous Substances Data)

Upstream product

• 28900-10-9 2-chloro-6-methylnicotinonitrile 
• 104-94-9 4-methoxy-aniline 

Downstream Products

• 95848-07-0 1-(4-Methoxy-phenyl)-2,7-dimethyl-1H-pyrido[2,3-d]pyrimidin-4-one 
• 82756-17-0 7-Methoxy-2-methyl-10H-benzo[b][1,8]naphthyridin-5-one 
• 82756-14-7 2-(4-Methoxy-phenylamino)-6-methyl-nicotinamide 
• 95848-02-5 N-(3-Cyano-6-methyl-pyridin-2-yl)-N-(4-methoxy-phenyl)-acetamide 

Relevant articles and documents

Reactions of 6-Methyl- and 4,6-Dimethyl-2-arylaminonicotinonitriles with Acids

A substituted nicotinic acid is formed when 6-methyl-2-anilinonicotinonitrile is refluxed with concentrated hydrochloric acid, whereas 4,6-dimethyl-2-anilinonicotinonitrile is not hydrolyzed under these and more severe conditions because of steric hindrance.Both of these nitriles undergo cyclization to 10-aminobenzo-1,8-naphthyridine derivatives under the influence of concentrated sulfuric acid.When 6-methyl-2-arylaminonicotinonitriles are heated in polyphosphoric acid (PPA), they are converted to 2-arylaminonicotinic acid amides and, in part, to benzo-1,8-naphthyrid-10-one derivatives, while 4,6-dimethyl-2-arylaminonicotinonitriles are converted primarily to 10-aminobenzo-1,8-naphthyridines.