82799-14-2

Basic information

• Product Name: 5-Hydroxytricyclo[8.2.1.03,8]trideca-3,5,7-trien-13-one
• Synonyms: 5-Hydroxytricyclo[8.2.1.03,8]trideca-3,5,7-trien-13-one
• CAS NO: 82799-14-2
• Molecular Formula: C₁₃H₁₄O₂
• Molecular Weight: 202.25
• Mol File: 82799-14-2.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-Hydroxytricyclo[8.2.1.03,8]trideca-3,5,7-trien-13-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Hydroxytricyclo[8.2.1.03,8]trideca-3,5,7-trien-13-one(82799-14-2)
• EPA Substance Registry System: 5-Hydroxytricyclo[8.2.1.03,8]trideca-3,5,7-trien-13-one(82799-14-2)

Safety Data

• Hazardous Substances Data: 82799-14-2(Hazardous Substances Data)

Upstream product

• 54962-18-4 5,6,7,8,9,10-hexahydro-6,9-methanobenzocyclo-octen-11-one 
• 82799-17-5 2-amino-11-oxo-5,6,7,8,9,10-hexahydro-6,9-methanobenzocyclooctene 
• 82799-15-3 2-nitro-11-oxo-5,6,7,8,9,10-hexahydro-6,9-methanobenzocyclooctene 

Downstream Products

• 423168-79-0 5-benzyloxy-tricyclo[8.2.1.0^3,8]trideca-3,5,7-trien-13-one 
• 82838-31-1 (1R,10S,13R)-13-Amino-tricyclo[8.2.1.0^3,8]trideca-3,5,7-trien-5-ol 
• 849549-77-5 C₂₀H₂₀O₂ 
• 362657-45-2 5-[2-(4-fluoro-phenoxy)-ethoxy]-tricyclo[8.2.1.03,8]trideca-3⁽⁸⁾,4,6-trien-13-one 

Relevant articles and documents

Cyclic sulfamide γ-secretase inhibitors

A novel series of N-alkyl-substituted cyclic sulfamides were developed from a screening hit. Chemistries were developed which allowed surveys of N-alkyl groups and amines resulting in the identification of N-trifluoroethyl- substituted cyclic sulfamides with good in vitro and in vivo γ-secretase activity. One compound with subnanomolar activity elicited a reduction in brain Aβ40 after oral dosing in APP-YAC mice.

Derivatives of 2-hydroxy-6,9-methano-11-amino-5,6,7,8,9,10-hexahydro-benzocyclooctene

Novel amino derivatives of 2-hydroxy-6,9-methano-11-amino-5,6,7,8,9,10-hexahydro-benzocyclooctenes, methods for their preparation, and their use as effective analgesic agents is described.