849549-77-5Relevant articles and documents
GAMMA-SECRETASE INHIBITORS
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Page/Page column 31, (2008/06/13)
Compounds of formula: (I) are potent inhibitors of gamma-secretase and hence find use in treatment or prevention of diseases associated with deposition of β-amyloid.
ALKENYL-SUBSTITUTED SPIROCYCLIC SULFAMIDES AS INHIBITORS OF GAMMA-SECRETASE
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Page/Page column 20, (2010/02/07)
Compounds of formula (I) are disclosed: wherein R4 is an alkenyl group of defined structure. The compounds inhibit gamma-secretase, and hence are useful for treatment of Alzheimer's disease.