82830-18-0Relevant articles and documents
Enantiomers of 7-(2,3-Epoxypropoxy)actinomycin D as Dual-Action DNA-Acting Antitumor Agents
Sengupta, Sisir K.,Rosenbaum, David P.,Sehgal, Raj K.,Almassian, Bijan,Blondin, Joanne
, p. 1540 - 1547 (2007/10/02)
Enantiomeric forms of (+/-)-EPA have been synthesized; these are (R)-(+)- and (S)-(-)-EPA, which are active against a range of actinomycin resistant and marginally resposive tumors.The (R)-(+) enantiomer is unif