82833-71-4

Basic information

• Product Name: (E)-3-phenyl-1-(3-thienyl)phenylprop-2-en-1-one
• Synonyms: (E)-3-phenyl-1-(3-thienyl)phenylprop-2-en-1-one
• CAS NO: 82833-71-4
• Molecular Weight: 214.288
• Mol File: 82833-71-4.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: (E)-3-phenyl-1-(3-thienyl)phenylprop-2-en-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-3-phenyl-1-(3-thienyl)phenylprop-2-en-1-one(82833-71-4)
• EPA Substance Registry System: (E)-3-phenyl-1-(3-thienyl)phenylprop-2-en-1-one(82833-71-4)

Safety Data

• Hazardous Substances Data: 82833-71-4(Hazardous Substances Data)

Upstream product

• 10486-61-0 3-thienyl iodide 
• 100-42-5 styrene 
• 201230-82-2 carbon monoxide 
• 1468-83-3 1-(thiophen-3-yl)-ethanone 
• 100-52-7 benzaldehyde 

Downstream Products

• 86022-38-0 ((2S,3R)-3-Phenyl-oxiranyl)-thiophen-3-yl-methanone 

Relevant articles and documents

Borane-Catalyzed, Chemoselective Reduction and Hydrofunctionalization of Enones Enabled by B-O Transborylation

The use of stoichiometric organoborane reductants in organic synthesis is well established. Here these reagents have been rendered catalytic through an isodesmic B-O/B-H transborylation applied in the borane-catalyzed, chemoselective alkene reduction and formal hydrofunctionalization of enones. The reaction was found to proceed by a 1,4-hydroboration of the enone and B-O/B-H transborylation with HBpin, enabling catalyst turnover. Single-turnover and isotopic labeling experiments supported the proposed mechanism of catalysis with 1,4-hydroboration and B-O/B-H transborylation as key steps.

Synthesis of symmetrical and unsymmetrical triarylpyrylium ions: Via an inverse electron demand Diels-Alder reaction

BF3·OEt2 mediated inverse electron demand Diels-Alder (IEDDA) reaction of chalcones with aryl acetylenes is reported for the synthesis of symmetrical and unsymmetrical 2,4,6-triarylpyrylium ions. The protocol provides an effective one-pot method for the utilization of readily available simple substrates under mild reaction conditions leading to a diverse array of pyrylium ions in moderately good yield.

Cyclohexenones through addition of ethyl acetoacetate to 3-aryl-1-(thiophen-3-yl)prop-2-en-1-one derivatives

Chalcone derivatives 3a-i containing a thiophene ring were prepared by the condensation of 1-(thiophen-3-yl)ethanone with aromatic aldehydes in excellent yields. The Michael addition of ethyl acetoacetate 4 to chalcone derivatives 3a-i resulted in the for