82945-11-7

Basic information

• Product Name: Phosphine oxide, (1,1-dimethylethyl)phenyl-, (1R)-
• CAS NO: 82945-11-7
• Molecular Formula: C10H15OP
• Molecular Weight: 182.202
• Mol File: 82945-11-7.mol
• Article Data: 42

Chemical Properties

• CAS DataBase Reference: Phosphine oxide, (1,1-dimethylethyl)phenyl-, (1R)-(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphine oxide, (1,1-dimethylethyl)phenyl-, (1R)-(82945-11-7)
• EPA Substance Registry System: Phosphine oxide, (1,1-dimethylethyl)phenyl-, (1R)-(82945-11-7)

Safety Data

• Hazardous Substances Data: 82945-11-7(Hazardous Substances Data)

Upstream product

• 824-72-6 P,P-dichlorophenylphosphine oxide 
• 677-22-5 tert-butylmagnesium chloride 
• 82220-43-7 tert-butylphenylphosphinic methanesulfonic anhydride 
• 4923-85-7 tert-butylphenylphosphinic acid chloride 
• 18351-72-9 1,2-di-tert-butyl-1,2-diphenyldiphosphane 1,2-dioxide 
• 41308-87-6 tert-butylphenylphosphinic acid anhydride 
• 98976-30-8 tert-Butylphenylphosphine oxide 
• 890415-62-0 (+)-1-(N-benzylamino)-1-(4-pyridyl)-(S)-methyl-tert-butylphenyl-(S)-phosphine oxide 
• 67-56-1 methanol 
• 29949-69-7 tert-butylchlorophenylphosphane 
• 3554-09-4 C₁₇H₁₅OSi^(1-)*K⁽¹⁺⁾ 
• 644-97-3 Dichlorophenylphosphine 
• 594-19-4 tert.-butyl lithium 
• 1619925-49-3 (-)-adamantyl hydrogenphenylphosphinate 

Downstream Products

• 72170-79-7 1,2-di-t-butyl-1,2-diphenyldiphosphane monoxide 
• 124081-67-0 trans-1-(tert-butylphenylphosphinyl)-2-(diphenylphosphinyl)ethene 
• 123474-02-2 C₁₉H₂₆O₂P₂ 
• 123474-02-2 C₁₉H₂₆O₂P₂ 
• 98933-82-5 (R_p)-[(tert-butyl)(phenyl)phosphinoyl]acetic acid menthyl ester 
• 98933-81-4 (S_p)-[(tert-butyl)(phenyl)phosphinoyl]acetic acid menthyl ester 
• 107487-23-0 (-)-α-naphthylphenylmethylsilyl t-butylphenylphosphinite 
• 124081-68-1 (-)-R,S-trans-1-(tert-butylphenylphosphinyl)-2-(methylphenylphosphinyl)ethene 
• 124081-68-1 (-)-S,S-trans-1-(tert-butylphenylphosphinyl)-2-(methylphenylphosphinyl)ethene 
• 92465-79-7 (tert-Butyl-chloromethyl-phosphinoyl)-benzene 
• 6057-79-0 (S)-(-)-t-butyl(phenyl)phosphine oxide 
• 82945-11-7 (R_p)-t-butyl(phenyl)phosphine oxide 
• 133201-82-8 (2-butenyl)-tert-butyl-phenyl phosphine oxide 

Relevant articles and documents

Method for simultaneously synthesizing phosphine chiral center second-level/third-level phosphine oxide compound under catalysis of palladium/chiral ligand

The invention discloses a method for simultaneously synthesizing phosphine chiral center second-level/third-level phosphine oxide compounds under catalysis of palladium/chiral ligands. The method comprises the following steps: in the presence of an organic solvent and an additive, carrying out kinetic resolution reaction on racemic secondary phosphine oxide as shown in a formula I and an alkylating reagent as shown in a formula II under the catalysis of a palladium catalyst/chiral ligand Xiao-Phos to obtain phosphine chiral center secondary phosphine oxide as shown in a formula III and a phosphine chiral center tertiary phosphine oxide compound as shown in a formula IV, wherein a reaction formula is shown as a formula (a). The raw materials are stable and easy to obtain, the method is simple, and the substrate application range is wide. According to the invention, an efficient route with atom economy is provided for kinetic resolution of racemic secondary phosphine oxide and preparation of a phosphine chiral center compound, the follow-up synthesis application of the two products with high optical activity is expanded, and the synthetic method provided by the invention has very high practical application value.

Palladium/Xiao-Phos-Catalyzed Kinetic Resolution of sec-Phosphine Oxides by P-Benzylation

P-stereogenic tert- and sec-phosphines have wide applications in asymmetric catalysis, materials, and pharmaceutical chemistry, however, their practical synthesis still constitutes a significant challenge. Herein, a successful kinetic resolution of rac-se

General and Stereoselective Method for the Synthesis of Sterically Congested and Structurally Diverse P-Stereogenic Secondary Phosphine Oxides

A general and efficient method for the synthesis of bulky and structurally diverse P-stereogenic chiral secondary phosphine oxides (SPOs) by using readily available chiral amino alcohol templates is described. These chiral SPOs could be used as chiral building blocks for the synthesis of difficult-to-access bulky P-stereogenic phosphine compounds or ligands for organic catalysis.