82959-82-8

Basic information

• Product Name: (2R,3R,4S)-2-Phenyl-pyrrolidine-3,4-dicarboxylic acid dimethyl ester
• CAS NO: 82959-82-8
• Molecular Weight: 263.293
• Mol File: 82959-82-8.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: (2R,3R,4S)-2-Phenyl-pyrrolidine-3,4-dicarboxylic acid dimethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3R,4S)-2-Phenyl-pyrrolidine-3,4-dicarboxylic acid dimethyl ester(82959-82-8)
• EPA Substance Registry System: (2R,3R,4S)-2-Phenyl-pyrrolidine-3,4-dicarboxylic acid dimethyl ester(82959-82-8)

Safety Data

• Hazardous Substances Data: 82959-82-8(Hazardous Substances Data)

Upstream product

• 90606-10-3 (E)-N-(phenylmethylene)-1-(trimethylsilyl)methylamine 
• 624-48-6 dimethyl cis-but-2-ene-1,4-dioate 
• 57402-97-8 N-<(trimethylsilyl)methyl>benzaldimine 
• 624-49-7 dimethylfumarate 
• 109-69-3 n-Butyl chloride 
• 778-28-9 butyl para-toluenesulfonate 
• 542-69-8 1-iodo-butane 
• 109-65-9 1-bromo-butane 
• 82959-82-8 dimethyl 2-phenyl-3,4-pyrrolidinedicarboxylate 
• 82959-80-6 (2R,3R,4R)-2-Phenyl-pyrrolidine-1,3,4-tricarboxylic acid 1-benzyl ester 3,4-dimethyl ester 
• 82959-80-6 (2S,3R,4R)-2-Phenyl-pyrrolidine-1,3,4-tricarboxylic acid 1-benzyl ester 3,4-dimethyl ester 
• 82959-80-6 (2R,3S,4S)-2-Phenyl-pyrrolidine-1,3,4-tricarboxylic acid 1-benzyl ester 3,4-dimethyl ester 
• 100-52-7 benzaldehyde 

Downstream Products

• 94191-22-7 (3R,4R)-1-Butyl-2-phenyl-pyrrolidine-3,4-dicarboxylic acid dimethyl ester 
• 82959-80-6 (2R,3R,4R)-2-Phenyl-pyrrolidine-1,3,4-tricarboxylic acid 1-benzyl ester 3,4-dimethyl ester 
• 82959-80-6 (2S,3R,4R)-2-Phenyl-pyrrolidine-1,3,4-tricarboxylic acid 1-benzyl ester 3,4-dimethyl ester 
• 79962-71-3 (2R,3R,4S)-1-Benzoyl-2-phenyl-pyrrolidine-3,4-dicarboxylic acid dimethyl ester 
• 79962-71-3 (2R,3S,4R)-1-Benzoyl-2-phenyl-pyrrolidine-3,4-dicarboxylic acid dimethyl ester 
• 79962-71-3 (2R,3S,4S)-1-Benzoyl-2-phenyl-pyrrolidine-3,4-dicarboxylic acid dimethyl ester 
• 82959-82-8 (2S,3R,4R)-2-Phenyl-pyrrolidine-3,4-dicarboxylic acid dimethyl ester 
• 82959-82-8 (2R,3R,4R)-2-Phenyl-pyrrolidine-3,4-dicarboxylic acid dimethyl ester 

Relevant articles and documents

One-Pot Synthesis of N-Alkylpyrrolidines by 1,3-Dipolar Cycloaddition

N-Alkylpyrrolidines were obtained by one-pot synthesis through 1,3-dipolar cycloaddition of the N-alkylazomethine ylide intermediates generated from N-(benzylidene)trimethylsilylmethylamine and alkyl halide or tosylate.

Trimethylsilyl Triflate-Catalyzed 1,3-Dipolar Cycloaddition Leading to N-Unsubstituted Pyrrolidines

Dipolar cycloaddition of an intermediary N-trimethylsilyltrimethylsilylmethyliminium salt formed from N-(benzylidene)trimethylsilylmethylamine by the catalytical action of trimethylsilyl triflate to conjugated alkene or alkyne gave N-unsubstituted pyrroli

WATER-INDUCED FORMATION OF AZOMETHINE YLIDE 1,3-DIPOLE. STEREOSPECIFIC AND REGIOSELECTIVE CYCLOADDITION REACTIONS

An N-(trimethylsilylmethyl)imine generates the azomethine ylide 1,3-dipole of nonstabilized type, when treated with water, which cycloadds to olefinic dipolarophiles in a stereospecific and regioselective manner.