832-92-8

Basic information

• Product Name: MESCALINE HYDROCHLORIDE
• Synonyms: MESCALINE HYDROCHLORIDE;3,4,5-trimethoxy-beta-phenylethylaminehydrochloride;3,4,5-trimethoxyphenethylaminehydrochloride;3,4,5-trimethoxy-phenethylaminhydrochloride;mescaline hcl methanol solution;mescaline hcl--dea schedule I item;Mescalin, Mescaline, Mezcaline, NSC 30419, TMPEA, 3,4,5-Trimethoxybenzeneethanamine, Hydrochloride;2-(3,4,5-TRIMETHOXYPHENYL)ETHYLAMINEHYDROCHLORIDE
• CAS NO: 832-92-8
• Molecular Formula: C₁₁H₁₇NO₃*ClH
• Molecular Weight: 247.72
• EINECS: 212-626-3
• Product Categories: Amines;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 832-92-8.mol
• Article Data: 2

Chemical Properties

• Melting Point: 180-182°C
• Boiling Point: 312.1 °C at 760 mmHg
• Flash Point: 9℃
• Appearance: /
• Vapor Pressure: 0.000541mmHg at 25°C
• Storage Temp.: 2-8°C
• CAS DataBase Reference: MESCALINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: MESCALINE HYDROCHLORIDE(832-92-8)
• EPA Substance Registry System: MESCALINE HYDROCHLORIDE(832-92-8)

Safety Data

• Hazard Codes: Xn,T,F
• Statements: 22-39/23/24/25-36/38-23/24/25-11
• Safety Statements: 22-26-36-45-36/37-24-16-7
• RIDADR: UN 1230 3/PG 2
• WGK Germany: 3
• RTECS: SI2800000
• Hazardous Substances Data: 832-92-8(Hazardous Substances Data)

Usage

Chemical Properties

Off-White Solid

Uses

Different sources of media describe the Uses of 832-92-8 differently. You can refer to the following data:
1. Mescaline is a psychedelic phenethylamine that is found naturally in plants predominantly in the cactus family, including peyote (L. williamsii). It binds and activates serotonin receptors, with preference for 5-HT2A over 5-HT2C (EC50 = 4 and 24 μM, respectively). This product is intended for research and forensic purposes.[Cayman Chemical]
2. Psychotomimetic alkaloid isolated from peyote (mescal buttons), the flowering heads of Lophophora williamsii (Lemaire). Controlled substance (hallucinogen)

InChI:InChI=1/C11H17NO3.ClH/c1-13-9-6-8(4-5-12)7-10(14-2)11(9)15-3;/h6-7H,4-5,12H2,1-3H3;1H

Upstream product

• 6316-70-7 3,4,5-trimethoxy-β-nitrostyrene 
• 25173-72-2 3-(3,4,5-trimethoxyphenyl)propanoic acid 
• 1436392-06-1 benzyl 3,4,5-trimethoxyphenethylcarbamate 

Downstream Products

• 18066-77-8 N-[2-(3,4,5-trimethoxyphenyl)ethyl]phthalimide 
• 37785-48-1 2-(3,4,5-trimethoxyphenyl)ethanol 
• 529-91-9 dimethyl-(3,4,5-trimethoxy-phenethyl)-amine 
• 1204357-69-6 1-(2,6-dichlorophenyl)-6,7,8-trimethoxy-3,4-dihydroisoquinoline 
• 1383540-87-1 1-(3,5-dinitrophenyl)-6,7,8-trimethoxy-3,4-dihydroisoquinoline hydrochloride 
• 1383540-88-2 6,7,8-trimethoxy-1-(4-nitrophenyl)-3,4-dihydroisoquinoline hydrochloride 
• 1204357-73-2 2-methoxy-5-(6,7,8-trimethoxy-3,4-dihydroisoquinolin-1-yl)phenol 
• 1383540-90-6 2-methoxy-5-(6,7,8-trimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)phenol 
• 1383540-91-7 6,7,8-trimethoxy-1-(4-methoxy-3-nitrophenyl)-1,2,3,4-tetrahydroisoquinoline 
• 1204357-83-4 1-(4-fluorophenyl)-6,7,8-trimethoxy-1,2,3,4-tetrahydroisoquinoline 
• 1204357-81-2 1-(4-fluorophenyl)-6,7,8-trimethoxyisoquinoline 
• 1383540-81-5 6,7,8-trimethoxy-1-phenyl-3,4-dihydroisoquinoline hydrochloride 
• 1383540-82-6 6,7,8-trimethoxy-1-(4-methoxyphenyl)-3,4-dihydroisoquinoline hydrochloride 
• 1204357-74-3 1-(3,4-dimethoxyphenyl)-6,7,8-trimethoxy-3,4-dihydroisoquinoline 

Relevant articles and documents

Synthesis and carbonic anhydrase inhibitory properties of sulfamides structurally related to dopamine

A series of novel sulfamides incorporating the dopamine scaffold were synthesized. Reaction of amines and tert-butyl-alcohol/benzyl alcohol in the presence of chlorosulfonyl isocyanate (CSI) afforded sulfamoyl carbamates, which were converted to the title compounds by treatment with trifluoroacetic acid or by palladium-catalyzed hydrogenolysis. Inhibition of six α-carbonic anhydrases (CAs, EC 4.2.1.1), that is, CA I, CA II, CA VA, CA IX, CA XII and CA XIV, and two β-CAs from Candida glabrata (CgCA) and Mycobacterium tuberculosis (Rv3588) with these sulfamides was investigated. All CA isozymes were inhibited in the low micromolar to nanomolar range by the dopamine sulfamide analogues. Kis were in the range of 0.061-1.822 μM for CA I, 1.47-2.94 nM for CA II, 2.25-3.34 μM for CA VA, 0.041-0.37 μM for CA IX, 0.021-1.52 μM for CA XII, 0.007-0.219 μM for CA XIV, 0.35-5.31 μM for CgCA and 0.465-4.29 μM for Rv3588. The synthesized sulfamides may lead to inhibitors targeting medicinally relevant CA isoforms with potential applications as antiepileptic, antiobesity antitumor agents or anti-infective.