83419-12-9

Basic information

• Product Name: 4(1H)-Pyrimidinone, 5-iodo-6-methyl-2-phenyl-
• CAS NO: 83419-12-9
• Molecular Formula: C11H9IN2O
• Molecular Weight: 312.11
• Mol File: 83419-12-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 4(1H)-Pyrimidinone, 5-iodo-6-methyl-2-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 4(1H)-Pyrimidinone, 5-iodo-6-methyl-2-phenyl-(83419-12-9)
• EPA Substance Registry System: 4(1H)-Pyrimidinone, 5-iodo-6-methyl-2-phenyl-(83419-12-9)

Safety Data

• Hazardous Substances Data: 83419-12-9(Hazardous Substances Data)

Upstream product

• 13514-79-9 6-methyl-2-phenyl-3H-pyrimidin-4-one 
• 618-39-3 benzamidin 
• 13514-79-9 6-methyl-2-phenylpyrimidin-4-ol 

Downstream Products

• 83410-17-7 4-Chloro-5-iodo-6-methyl-2-phenyl-pyrimidine 
• 929880-36-4 acetic acid 5-iodo-6-methyl-2-phenyl-pyrimidin-4-yl ester 
• 1236282-90-8 2-[butyl-(5-iodo-6-methyl-2-phenylpyrimidin-4-yl)-amino]-N-[2-(3,4-dimethoxyphenyl)-ethyl]-acetamide 
• 1461736-41-3 2-[5-benzyl-6-(4-chlorophenyl)-4-methyl-2-phenylpyrrolo[2,3-d]pyrimidin-7-yl]-4-methylpentanoic acid 4-methoxybenzylamide 
• 1461736-27-5 2-[(4-chlorobenzyl)-(6-methyl-2-phenyl-5-phenylethynylpyrimidin-4-yl)-amino]-4-methylpentanoic acid 4-methoxybenzylamide 
• 1461736-12-8 2-((4-chlorobenzyl)-(5-iodo-6-methyl-2-phenylpyrimidin-4-yl)amino)-N-(4-methoxybenzyl)-4-methylpentanamide 
• 1372134-74-1 N-(4-chlorobenzyl)-4-methyl-2-(4-methyl-2-phenylpyrido[2,3-d]pyrimidin-8(5H)-yl)pentanamide 
• 1372134-67-2 N-(4-chlorobenzyl)-2-(cyclopropyl(5-iodo-6-methyl-2-phenylpyrimidin-4-yl)amino)-4-methylpentanamide 
• 1372134-66-1 2-(cyclopropyl(5-iodo-6-methyl-2-phenylpyrimidin-4-yl)amino)-N-(4-methoxybenzyl)-2-(4-methoxyphenyl)acetamide 
• 1372134-73-0 N-(4-methoxybenzyl)-2-(4-methoxyphenyl)-2-(4-methyl-2-phenylpyrido[2,3-d]pyrimidin-8(5H)-yl)acetamide 
• 1272662-71-1 toluene-4-sulfonic acid 5-iodo-2-phenyll-6-methylpyrimidin-4-yl ester 
• 1272662-48-2 2-[(5-iodo-6-methyl-2-phenylpyrimidin-4-yl)-(5-methylfuran-2-ylmethyl)-amino]-4-methylpentanoic acid 4-chlorobenzylamide 
• 1272662-93-7 (E)-3-(7-benzyl-4-methyl-2-phenyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-propenal 
• 1272662-92-6 (E)-4-(4,7-dimethyl-2-phenyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-but-3-en-2-one 

Relevant articles and documents

Palladium catalyzed ring opening of furans as a route to α,β-unsaturated aldehydes

Furans may be ring opened via pallado-catalyzed reactions leading to α,β-unsaturated aldehydes and ketones tethered to indole and isoquinoline moieties. Besides their synthetic interest, these fragmentations bring interesting elements into the discussion

Synthesis of novel 5,6-substituted furo[2,3-d]pyrimidines via Pd-catalyzed cyclization of alkynylpyrimidinols with aryl iodides

A flexible method for the synthesis of 5,6-disubstituted furo[2,3-d]pyrimidine derivatives is described. The key step is a palladium-catalyzed arylative cyclization of alkynylpyrimidinols with various aryl iodides, which gave the title compounds in 36-75% yield.