929880-36-4Relevant articles and documents
Synthesis of novel 5,6-substituted furo[2,3-d]pyrimidines via Pd-catalyzed cyclization of alkynylpyrimidinols with aryl iodides
Liu, Zhende,Li, Dewen,Li, Shukun,Bai, Donglu,He, Xuchang,Hu, Youhong
, p. 1931 - 1936 (2007/10/03)
A flexible method for the synthesis of 5,6-disubstituted furo[2,3-d]pyrimidine derivatives is described. The key step is a palladium-catalyzed arylative cyclization of alkynylpyrimidinols with various aryl iodides, which gave the title compounds in 36-75% yield.