835-68-7

Basic information

• Product Name: Benzenemethanol, a-cyclohexyl-4-methoxy-
• CAS NO: 835-68-7
• Molecular Formula: C14H20O2
• Molecular Weight: 220.312
• Mol File: 835-68-7.mol
• Article Data: 17

Chemical Properties

• CAS DataBase Reference: Benzenemethanol, a-cyclohexyl-4-methoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, a-cyclohexyl-4-methoxy-(835-68-7)
• EPA Substance Registry System: Benzenemethanol, a-cyclohexyl-4-methoxy-(835-68-7)

Safety Data

• Hazardous Substances Data: 835-68-7(Hazardous Substances Data)

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 931-50-0 cyclohexylmagnesium bromide 
• 36140-19-9 dicyclohexylboron chloride 
• 297163-77-0 (4-methoxyphenyl)(ethyl)silanediol 
• 2043-61-0 cyclohexanecarbaldehyde 
• 626-62-0 Cyclohexyl iodide 
• 931-51-1 cyclohexylmagnesiumchloride 
• 542-18-7 cyclohexyl chloride 
• 5720-07-0 4-methoxyphenylboronic acid 
• 100-66-3 methoxybenzene 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 82303-13-7 (4-methoxyphenyl)zinc(II) bromide 
• 108-85-0 1-bromocyclohexane 
• 110-82-7 cyclohexane 

Downstream Products

• 92035-56-8 1-(4-Hydroxyphenyl)methylcyclohexane 
• 7469-80-9 cyclohexyl 4-methoxyphenyl ketone 
• 7577-08-4 1-(cyclohexylidenemethyl)-4-methoxy-benzene 
• 13724-70-4 1-(cyclohexylmethyl)-4-methoxybenzene 
• 100792-64-1 4-(chloro-cyclohexyl-methyl)-anisole 

Relevant articles and documents

Aminophenone compounds as well as preparation method and application thereof

The invention belongs to the technical field of medicinal chemistry, and particularly relates to aminophenone compounds as well as a preparation method and application thereof. The aminophenone compounds provided by the invention have a good inhibition effect on PDE4, also have good bioavailability, can be applied to preparation of drugs for treating PDE4-related diseases, and increase the optionsof drugs for treating PDE4-related diseases; and the effect of a part of the aminophenone compounds is equivalent to the effect of positive drugs, and the aminophenone compounds have good developmentpotential.

Lewis Acid Catalyzed Transfer Hydromethallylation for the Construction of Quaternary Carbon Centers

The design and gram-scale synthesis of a cyclohexa-1,4-diene-based surrogate of isobutene gas is reported. Using the highly electron-deficient Lewis acid B(C6F5)3, application of this surrogate in the hydromethallylation of electron-rich styrene derivatives provided sterically congested quaternary carbon centers. The reaction proceeds by C(sp3)?C(sp3) bond formation at a tertiary carbenium ion that is generated by alkene protonation. The possibility of two concurrent mechanisms is proposed on the basis of mechanistic experiments using a deuterated surrogate.

[Ir(COD)Cl]2/tris(2,4-di-t-butylphenyl)phosphite-catalyzed addition reactions of arylboronic acids with aldehydes

[Ir(COD)Cl]2/tris(2,4-di-t-butylphenyl)phosphite-catalyzed addition reactions of arylboronic acids with aldehydes were described. The Ir(I) catalyst, generated from [Ir(COD)Cl]2 and tris(2,4-di-t-butylphenyl)phosphite, was an efficient catalyst system for the addition reactions of a variety of arylboronic acids with aromatic and aliphatic aldehydes. The easy availability of the catalyst and good yields make these reactions potentially useful in organic synthesis.