837-66-1

Basic information

• Product Name: 3-Buten-2-one, 4,4-diphenyl-
• CAS NO: 837-66-1
• Molecular Formula: C16H14O
• Molecular Weight: 222.287
• Mol File: 837-66-1.mol
• Article Data: 51

Chemical Properties

• CAS DataBase Reference: 3-Buten-2-one, 4,4-diphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Buten-2-one, 4,4-diphenyl-(837-66-1)
• EPA Substance Registry System: 3-Buten-2-one, 4,4-diphenyl-(837-66-1)

Safety Data

• Hazardous Substances Data: 837-66-1(Hazardous Substances Data)

Upstream product

• 591-50-4 iodobenzene 
• 78-94-4 methyl vinyl ketone 
• 54166-20-0 3,3-diphenylcyclobutanone 
• 7721-58-6 3-methylamino-1-phenylbut-2-en-1-one 
• 29291-01-8 1,1-diphenyl-2-methyl-2-propen-1-ol 
• 15295-29-1 4,4-diphenyl-4-hydroxybut-2-ene 
• 119-61-9 benzophenone 
• 530-48-3 1,1-Diphenylethylene 
• 122408-62-2 2,2-dichloro-3,3-diphenylcyclobutanone 
• 914785-45-8 N-(4-methoxyphenyl)-N-methyl-3-phenylprop-2-ynamide 
• 111-34-2 -butyl vinyl ether 
• 836-87-3 1,1-diphenyl-2-butyn-1-ol 
• 100-58-3 phenylmagnesium bromide 
• 108-86-1 bromobenzene 

Downstream Products

• 81957-19-9 3-bromo-4,4-diphenyl-but-3-en-2-one 
• 104581-48-8 2-methyl-4,4-diphenylbut-3-en-2-ol 
• 37608-24-5 1-Diazo-4,4-diphenyl-but-3-en-2-one 
• 77915-31-2 1,1’-(3-methyl-1,3-butadienylidene)bis-benzene 
• 1263002-12-5 1-chloro-4-(4,4-diphenylbuta-1,3-dien-2-yl)benzene 
• 1263002-11-4 1-(4,4-diphenylbuta-1,3-dien-2-yl)-4-methoxybenzene 
• 1263002-13-6 5-(4,4-diphenylbuta-1,3-dien-2-yl)benzo[d][1,3]dioxole 
• 942517-67-1 (S)-4,4-diphenyl-2-hydroxybut-3-ene 
• 285566-28-1 (3E)-4-phenyl-3-penten-2-ol 
• 15295-29-1 4,4-diphenyl-4-hydroxybut-2-ene 
• 1415577-49-9 C₁₂H₁₄OS 
• 28191-98-2 3,4,4-triphenylbut-3-en-2-one 

Relevant articles and documents

Ring Cleavages in the Reductive Alkylation of Amines with 4-Oxo-6,6-diphenyl-tetrahydropyran-2-one

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Visible-Light-Induced Transition-Metal-Free Nitrogen-Centered Radical Strategy for the Synthesis of 2-Acylated 9 H-Pyrrolo[1,2- a]indoles

A convenient and efficient visible-light-induced tandem acylation/cyclization of N-propargylindoles with aryl- or alkyl-substituted acyl oxime esters for the synthesis of 2-acyl-substituted 9H-pyrrolo[1,2-a]indoles under transition-metal-free conditions, which proceeds via nitrogen-centered radical-mediated cleavage of the C-C σ-bond in acyl oxime esters, is established. The aryl or alkyl acyl radicals, which come from acyl oxime esters, attack the C-C triple bonds in N-propargylindoles and then go through intramolecular cyclization/isomerization.

Alcohol Dehydrogenases and N-Heterocyclic Carbene Gold(I) Catalysts: Design of a Chemoenzymatic Cascade towards Optically Active β,β-Disubstituted Allylic Alcohols

The combination of gold(I) and enzyme catalysis is used in a two-step approach, including Meyer–Schuster rearrangement of a series of readily available propargylic alcohols followed by stereoselective bioreduction of the corresponding allylic ketone intermediates, to provide optically pure β,β-disubstituted allylic alcohols. This cascade involves a gold N-heterocyclic carbene and an enzyme, demonstrating the compatibility of both catalyst types in aqueous medium under mild reaction conditions. The combination of [1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene][bis(trifluoromethanesulfonyl)-imide]gold(I) (IPrAuNTf2) and a selective alcohol dehydrogenase (ADH-A from Rhodococcus ruber, KRED-P1-A12 or KRED-P3-G09) led to the synthesis of a series of optically active (E)-4-arylpent-3-en-2-ols in good yields (65–86 %). The approach was also extended to various 2-hetarylpent-3-yn-2-ol, hexynol, and butynol derivatives. The use of alcohol dehydrogenases of opposite selectivity led to the production of both allyl alcohol enantiomers (93->99 % ee) for a broad panel of substrates.