839718-30-8

Basic information

• Product Name: 4-Isoxazolecarboxylic acid, 5-[4-[[(3-methoxy-3-oxopropyl)thio]methyl]phenyl]-, 1,1-dimethylethyl ester
• CAS NO: 839718-30-8
• Molecular Formula: C19H23NO5S
• Molecular Weight: 377.461
• Mol File: 839718-30-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-Isoxazolecarboxylic acid, 5-[4-[[(3-methoxy-3-oxopropyl)thio]methyl]phenyl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Isoxazolecarboxylic acid, 5-[4-[[(3-methoxy-3-oxopropyl)thio]methyl]phenyl]-, 1,1-dimethylethyl ester(839718-30-8)
• EPA Substance Registry System: 4-Isoxazolecarboxylic acid, 5-[4-[[(3-methoxy-3-oxopropyl)thio]methyl]phenyl]-, 1,1-dimethylethyl ester(839718-30-8)

Safety Data

• Hazardous Substances Data: 839718-30-8(Hazardous Substances Data)

Upstream product

• 839718-29-5 tert-butyl 3-(4-{[(3-methoxy-3-oxopropyl)thio]methyl}phenyl)-3-oxopropionate 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 73291-09-5 4-chloromethylbenzaldehyde 
• 16473-35-1 4-(hydroxymethyl)benzyl chloride 
• 34040-64-7 p-methyloxycarbonylbenzyl chloride 
• 839718-28-4 tert-butyl 3-hydroxy-3-(4-{[(3-methoxy-3-oxopropyl)thio]-methyl}phenyl)propionate 
• 946149-63-9 C₂₄H₄₀O₅SSi 
• 839718-27-3 tert-butyl 3-(tert-butyldimethylsilyl)oxy-3-(4-chloromethylphenyl)propionate 

Downstream Products

• 839718-31-9 5-(4-{[(3-methoxy-3-oxopropyl)thio]methyl}phenyl)isoxazole-4-carboxylic acid 
• 946149-64-0 methyl 3-(4-[4-[1-(2-chlorophenyl)ethoxycarbonylamino]-5-isoxazolyl]benzylsulfanyl)propionate 

Relevant articles and documents

Synthesis and evaluation of isoxazole derivatives as lysophosphatidic acid (LPA) antagonists

A series of isoxazole derivatives were synthesized and their antagonistic activities against LPA stimulation on both LPA1/CHO cells and rHSC cells were evaluated. Among them, 3-(4-{4-[1-(2-chloro-cyclopent-1-enyl)-ethoxycarbonylamino]-isoxazol-3- yl}-benzylsulfanyl)-propionic acid (34) showed the most potent activities.