840525-19-1

Basic information

• Product Name: L-Glutamic acid, N-[(phenylmethoxy)carbonyl]glycyl-L-prolyl-, 31-(phenylmethyl) ester
• CAS NO: 840525-19-1
• Molecular Formula: C27H31N3O8
• Molecular Weight: 525.558
• Mol File: 840525-19-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: L-Glutamic acid, N-[(phenylmethoxy)carbonyl]glycyl-L-prolyl-, 31-(phenylmethyl) ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Glutamic acid, N-[(phenylmethoxy)carbonyl]glycyl-L-prolyl-, 31-(phenylmethyl) ester(840525-19-1)
• EPA Substance Registry System: L-Glutamic acid, N-[(phenylmethoxy)carbonyl]glycyl-L-prolyl-, 31-(phenylmethyl) ester(840525-19-1)

Safety Data

• Hazardous Substances Data: 840525-19-1(Hazardous Substances Data)

Upstream product

• 1160-54-9 (2S)-1-(2-[[(benzyloxy)carbonyl]amino]acetyl)tetrahydro-1H-pyrrole-2-carboxylic acid 
• 13030-09-6 1-benzyl L-glutamate 
• 38417-02-6 N-(N-benzyloxycarbonyl-glycyl)-L-proline N-hydroxysuccinimidyl ester 

Downstream Products

• 840525-25-9 benzyl (2S)-N-[N-(N-benzyloxycarbonyl-glycyl)-L-prolyl]-2-amino-5-hydroxypentanoate 
• 840525-23-7 N-[N-(N-benzyloxycarbonyl-glycyl)-L-prolyl]-L-Nγ,Nγ-dimethyl-glutamine α-benzyl ester 
• 840525-21-5 N-[N-(N-benzyloxycarbonyl-glycyl)-L-prolyl]-L-Nγ-methyl-glutamine α-benzyl ester 

Relevant articles and documents

Synthesis and pharmacological evaluation of side chain modified glutamic acid analogues of the neuroprotective agent glycyl-L-prolyl-L-glutamic acid (GPE)

The synthesis of eight GPE* analogues, wherein the γ-carboxylic moiety of the glutamic residue has been modified, is described by coupling readily accessible N-benzyloxycarbonyl-glycyl-l-proline with various analogues of glutamic acid. Pharmacological evaluation of the novel compounds was undertaken to further understand the role of the glutamate residue on the observed neuroprotective properties of the endogenous tripeptide GPE.