84284-70-8

Basic information

• Product Name: 4'-BENZYLOXYPHENYL ACETYLENE
• Synonyms: 4-Benzyloxyphenyl acetylene;Benzene, 1-ethynyl-4-(phenylmethoxy)-;1-Ethynyl-4-(phenylmethoxy)benzene
• CAS NO: 84284-70-8
• Molecular Formula: C₁₅H₁₂O
• Molecular Weight: 208.25
• Product Categories: Miscellaneous
• Mol File: 84284-70-8.mol
• Article Data: 20

Chemical Properties

• Melting Point: 260 °C
• Boiling Point: 328.5 °C at 760 mmHg
• Flash Point: 148.7 °C
• Appearance: /
• Density: 1.09 g/cm³
• Vapor Pressure: 0.000361mmHg at 25°C
• Refractive Index: 1.597
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4'-BENZYLOXYPHENYL ACETYLENE(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-BENZYLOXYPHENYL ACETYLENE(84284-70-8)
• EPA Substance Registry System: 4'-BENZYLOXYPHENYL ACETYLENE(84284-70-8)

Safety Data

• Hazardous Substances Data: 84284-70-8(Hazardous Substances Data)

Usage

General Description

4'-Benzyloxyphenyl acetylene is a chemical compound with the molecular formula C16H14O. It is a member of the phenylacetylene family and contains a benzene ring with a benzyloxy group attached to the para position. 4'-BENZYLOXYPHENYL ACETYLENE is commonly used in organic synthesis and can undergo various chemical reactions, including alkyne addition and Sonogashira coupling. It is also used as a building block in the production of pharmaceuticals, agrochemicals, and other fine chemicals. Additionally, the benzyloxy group can be easily removed under mild conditions, making it a versatile intermediate in organic chemistry. Overall, 4'-benzyloxyphenyl acetylene is a valuable chemical reagent with a wide range of applications in the field of organic synthesis.

InChI:InChI=1/C15H12O/c1-2-13-8-10-15(11-9-13)16-12-14-6-4-3-5-7-14/h1,3-11H,12H2

Upstream product

• 83671-19-6 p-benzyloxyphenyl dichloroethylene 
• 340322-86-3 2-[4-(benzyloxy)phenyl]-1-ethynyl(trimethyl)silane 
• 540-38-5 p-Iodophenol 
• 19578-68-8 4-(4-benzyloxyphenyl) iodide 
• 100-39-0 benzyl bromide 
• 4397-53-9 p-benzyloxybenzaldehyde 
• 54696-05-8 4'-benzyloxy-acetophenone 
• 27491-70-9 dimethyl diazomethylphosphonate 
• 114943-73-6 2-(4-Benzyloxyphenyl)-1,1-dibromoethylene 
• 90965-06-3 dimethyl 1-(1-diazo-2-oxopropyl)phosphonate 
• 558-13-4 carbon tetrabromide 
• 123-08-0 4-hydroxy-benzaldehyde 
• 152915-78-1 C₁₈H₁₈O₂ 
• 766-98-3 1-ethynyl-4-fluorobenzene 

Downstream Products

• 84284-73-1 2-(4'-benzyloxyphenyl)-7-methoxybenzofuran-4-carbaldehyde 
• 16819-41-3 1,2-bis(4-benzyloxyphenyl)acetylene 
• 1030829-56-1 ethyl 3-[4-(benzyloxy)phenyl]prop-2-ynoate 
• 475560-82-8 2,5-bis[(4-benzyloxyphenyl)ethynyl]-3,4-dibromothiophene 
• 877058-67-8 7-benzyl-2-(4-benzyloxy-phenyl)-3-phenyl-7H-furo[2,3-b]pyridin-4-one 
• 941574-05-6 C₂₉H₂₄O₅S 
• 953414-66-9 C₂₀H₁₅BrN₂O 
• 941573-96-2 C₂₈H₂₁IO₅S 
• 877058-69-0 C₁₉H₁₃NO₃ 
• 877058-70-3 4-(4-chloro-3-phenyl-furo[2,3-b]pyridin-2-yl)-phenol 
• 877058-71-4 4-{2-[2-(4-hydroxy-phenyl)-3-phenyl-furo[2,3-b]pyridin-4-ylamino]-ethyl}-piperazine-1-carboxylic acid tert-butyl ester 
• 877058-78-1 4-(2-{2-[4-(2-morpholin-4-yl-ethoxy)-phenyl]-3-phenyl-furo[2,3-b]pyridin-4-ylamino}-ethyl)-piperazine-1-carboxylic acid tert-butyl ester 
• 877058-72-5 4-(2-{2-[4-(2-diisopropylamino-ethoxy)-phenyl]-3-phenyl-furo[2,3-b]pyridin-4-ylamino}-ethyl)-piperazine-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

Cu-mediated or metal-free alkylation of gem-dibromoalkenes with tertiary, secondary and primary alkyl Grignard reagents

A novel copper-mediated or transition-metal-free alkylation of gem-dibromoalkenes with tertiary, secondary and primary alkyl Grignard reagents was described. The outcomes of these reactions were found to be highly dependent on the reaction conditions and

SO2F2-Mediated Oxidative Dehydrogenation and Dehydration of Alcohols to Alkynes

Direct synthesis of alkynes from inexpensive, abundant alcohols was achieved in high yields (greater than 40 examples, up to 95% yield) through a SO2F2-promoted dehydration and dehydrogenation process. This straightforward transformation of sp3-sp3 (C-C) bonds to sp-sp (C=C) bonds requires only inexpensive and readily available reagents (no transition metals) under mild conditions. The crude alkynes are sufficiently free of impurities to permit direct use in further transformations, as illustrated by regioselective Huisgen alkyne-azide cycloaddition reactions with PhN3 to give 1,4-substituted 1,2,3-traiazoles (16 examples, up to 92% yield) and Sonogashira couplings (10 examples, up to 77% yield).

ANTIBACTERIAL AGENT

An antibacterial agent comprising a compound represented by the following general formula (I), which can exhibit potent antibacterial activity against bacteria that have acquired resistance to quinolones (in the formula, R1 and R4 re