844658-92-0

Basic information

• Product Name: 1H-Imidazole, 1-[(1R)-1-phenylethyl]-
• CAS NO: 844658-92-0
• Molecular Formula: C11H12N2
• Molecular Weight: 172.23
• Mol File: 844658-92-0.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 1H-Imidazole, 1-[(1R)-1-phenylethyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Imidazole, 1-[(1R)-1-phenylethyl]-(844658-92-0)
• EPA Substance Registry System: 1H-Imidazole, 1-[(1R)-1-phenylethyl]-(844658-92-0)

Safety Data

• Hazardous Substances Data: 844658-92-0(Hazardous Substances Data)

Usage

Chemical class

Imidazole class of chemicals

Chirality

Chiral compound

Applications

Medicinal chemistry, drug development, building block in the synthesis of pharmaceuticals, ligand in coordination chemistry of transition metals

Biological activity

Potential biological activity, ligand for various receptors, enzymes, and metal ions

Versatility

Potential applications in both chemical and biological research

Upstream product

• 33125-97-2 etomidate 
• 74-89-5 methylamine 
• 50-00-0 formaldehyd 
• 131543-46-9 Glyoxal 
• 3886-69-9 (R)-1-phenyl-ethyl-amine 
• 288-32-4 1H-imidazole 
• 1517-69-7 (R)-1-phenylethanol 

Downstream Products

• 1586754-56-4 (R)-3-phenyl-1-(1-phenylethyl)-1H-imidazol-3-ium tetrafluoroborate 
• 1446135-59-6 3-[bromo(phenyl)methyl]-1-((R)-1-phenylethyl)-1H-imidazol-3-ium bromide 

Relevant articles and documents

Chiral, bridged bis(imidazolin-2-ylidene) complexes of palladium

Varieties of chiral, bridged bisimidazolium salts as well as the synthesis of palladium complexes of general formula [bridge {over(NC(H) {double bond, long} C(H)N (R*) C, -)}2 PdBr2] with the corresponding chelating N-heterocyclic carbene ligands is reported. This is the first systematic study of chiral bis(imidazolin-2-ylidene)palladium(II) complexes bearing chiral groups on the endocyclic nitrogens. Structural proof of such a chiral palladium(II) complex is presented by way of an X-ray diffraction study of complex 3a.

Imidazolium-based chiral ionic liquids: Synthesis and application

Synthesis of chiral ionic liquids containing an imidazole nucleus and chiral centers on N-substituents is reported. [(2S,3S)-2,3-Dihydroxybutane-1,4- bis(3-butylimidazolium)]-[bis(trifluoromethanesulfonyl)amide]2 and [(4S,5S)-2-phenyl-1,3-dioxo

Bridged imidazolium salts used as precursors for chelating carbene complexes of palladium in the Mizoroki-Heck reaction

A variety of chiral and achiral imidazolium salts is synthesized. Methylene-, ethylene-, propylene- and pyridinyl-bridged bis(imidazolium) halides are used to generate the respective free chelating carbenes. The synthesis of palladium complexes of general formula [cis-CH2{NC(H)=C(H)N(R)C} 2PdX2] with these chelating N-heterocyclic carbene ligands is reported. Structural proofs of complexes 28 and 46 are represented by X-ray diffraction studies. Catalytic applications in the Mizoroki-Heck reaction are presented. Georg Thieme Verlag Stuttgart.