845438-83-7

Basic information

• Product Name: 3-(Benzyloxy)-8-methoxy-6H-benzo[c]chromen-6-one
• Synonyms: 3-(Benzyloxy)-8-methoxy-6H-benzo[c]chromen-6-one
• CAS NO: 845438-83-7
• Molecular Weight: 332.356
• Mol File: 845438-83-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-(Benzyloxy)-8-methoxy-6H-benzo[c]chromen-6-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(Benzyloxy)-8-methoxy-6H-benzo[c]chromen-6-one(845438-83-7)
• EPA Substance Registry System: 3-(Benzyloxy)-8-methoxy-6H-benzo[c]chromen-6-one(845438-83-7)

Safety Data

• Hazardous Substances Data: 845438-83-7(Hazardous Substances Data)

Upstream product

• 22921-68-2 2-bromo-5-methoxy-benzoic acid 
• 108-46-3 recorcinol 
• 35233-17-1 3-hydroxy-8-methoxy-6H-dibenzo-[b,d]pyran-6-one 
• 100-39-0 benzyl bromide 

Downstream Products

• 845440-30-4 1-[2-(4-{[2-(tert-butyl-dimethyl-silanyloxy)-7-triisopropylsilanyloxy-10H-9-thia-phenanthren-10-yl]-triethylsilanyloxy-methyl}-phenoxy)-ethyl]-pyrrolidine 
• 845439-81-8 [2-(tert-butyl-dimethyl-silanyloxy)-7-triisopropylsilanyloxy-10H-9-thia-phenanthren-10-yl]-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-methanol 
• 845439-90-9 [2-(tert-butyl-dimethyl-silanyloxy)-7-triisopropylsilanyloxy-10H-9-thia-phenanthren-10-yl]-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-methanol 
• 845439-02-3 dimethyl-thiocarbamic acid O-(4-benzyloxy-2'-diethylcarbamoyl-4'-methoxy-biphenyl-2-yl) ester 
• 845439-13-6 dimethyl-thiocarbamic acid S-(4-benzyloxy-2'-diethylcarbamoyl-4'-methoxy-biphenyl-2-yl) ester 
• 845439-23-8 7-benzyloxy-2-methoxy-9-thia-phenanthren-10-one 
• 845438-93-9 4'-benzyloxy-2'-hydroxy-4-methoxy-biphenyl-2-carboxylic acid diethylamide 

Relevant articles and documents

Design, synthesis, and biological evaluation of novel 6h-benzo[c]chromen-6-one derivatives as potential phosphodiesterase ii inhibitors

Urolithins (hydroxylated 6H-benzo[c]chromen-6-ones) are the main bioavailable metabolites of ellagic acid (EA), which was shown to be a cognitive enhancer in the treatment of neurodegenerative diseases. As part of this research, a series of alkoxylated 6H-benzo[c]chromen-6-one derivatives were designed and synthesized. Furthermore, their biological activities were evaluated as potential PDE2 inhibitors, and the alkoxylated 6H-benzo[c]chromen-6-one derivative 1f was found to have the optimal inhibitory potential (IC50: 3.67 ± 0.47 μM). It also exhibited comparable activity in comparison to that of BAY 60-7550 in vitro cell level studies.