845439-81-8Relevant articles and documents
Estrogen receptor ligands. 12. Synthesis of the major metabolites of an ERα-selective, dihydrobenzoxathiin antagonist for osteoporosis
Kim, Seongkon,Wu, Jane Y.,Zhang, Zhoupeng,Tang, Wei,Doss, George A.,Dean, Brian J.,DiNinno, Frank,Hammond, Milton L.
, p. 411 - 414 (2007/10/03)
(Chemical Equation Presented) During the course of drug metabolism studies, a major metabolite of compound 1 was detected in rhesus monkeys and assigned structure 4. The intriguing biotransformation of 1 leading to 4 was confirmed by a 19-step total synth