846539-19-3

Basic information

• Product Name: Silane, trimethyl[[4-[[(1-methyl-2-propynyl)oxy]methyl]phenyl]methyl]-
• CAS NO: 846539-19-3
• Molecular Formula: C15H22OSi
• Molecular Weight: 246.425
• Mol File: 846539-19-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Silane, trimethyl[[4-[[(1-methyl-2-propynyl)oxy]methyl]phenyl]methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Silane, trimethyl[[4-[[(1-methyl-2-propynyl)oxy]methyl]phenyl]methyl]-(846539-19-3)
• EPA Substance Registry System: Silane, trimethyl[[4-[[(1-methyl-2-propynyl)oxy]methyl]phenyl]methyl]-(846539-19-3)

Safety Data

• Hazardous Substances Data: 846539-19-3(Hazardous Substances Data)

Upstream product

• 17993-96-3 p-<(Trimethylsilyl)methyl>benzyl alcohol 
• 846539-14-8 4-[(trimethylsilyl)methyl]benzyl 2,2,2-trichloroethanimidoate 
• 2028-63-9 but-3-yn-2-ol 

Downstream Products

• 109088-53-1 p-<(trimethylsilyl)methyl>benzaldehyde 
• 2028-63-9 but-3-yn-2-ol 

Relevant articles and documents

NOVEL PROTECTING REAGENTS, PROTECTING GROUPS AND METHODS OF FORMING AND USING THE SAME

New protecting reagents are provided that allow for the selective placement of a new protecting group onto a reactive site of a multifunctional compound. The reagents are 2, 3, and 4-trialkylsilylxylyl, triarylsilylxylyl or a combination of alkyl-aryl silylxylyl reagents (TIX reagents), which carry a TIX protecting group for protecting alcohols as ethers, urethanes, carbonates, acetals; amines as carbamates or ureas; and thiols as ethers or esters. The invention also provides methods of forming the 2, 3, and 4-TIX reagents; introducing the TIX protecting groups to molecules bearing hydroxyl groups, amine groups, or thiol groups; methods of removing the TIX protecting groups; and intermediate compounds formed during any one of these methods. The invention further provides methods useful in producing epothilones and analogs and derivatives thereof.